Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA.
Department of Orthopedics, University of Illinois at Chicago, Chicago, Illinois, USA.
J Orthop Res. 2021 Jun;39(6):1236-1244. doi: 10.1002/jor.24856. Epub 2020 Sep 21.
Physical activity is important for physical function and pain relief in people with lower extremity osteoarthritis (OA). Unfortunately, people with OA are not as active as their peers without OA. The objective of this study was to determine whether aerobic capacity and fatigability are associated with physical activity in women with hip OA. We conducted a cross-sectional analysis of 36 women with hip OA. We assessed aerobic fitness as predicted VO max from a 6-min walk test. We assessed fatigability using a treadmill test. Finally, we assessed self-reported physical activity using the UCLA activity scale and quantified steps per day and activity intensity using accelerometers. We used Pearson correlations to determine associations. We used regression analysis to determine whether fatigability mediated the association between aerobic fitness and physical activity. On average, subjects were moderately active via the UCLA score (5.2 ± 1.3 out of 10). Aerobic fitness (R = 0.582, p < .001) and fatigability (R = 0.516, p =.003) were significantly correlated with UCLA scores. However, aerobic fitness was the best predictor of UCLA scores, as well as sedentary time, and time spent in light activity. Fatigability was not a mediator between aerobic fitness and UCLA scores. Aerobic fitness and fatigability may be modifiable barriers to physical activity in people with OA. Future interventional studies should examine whether improving aerobic fitness improves physical activity or fatigability.
身体活动对于下肢骨关节炎（OA）患者的身体功能和缓解疼痛很重要。不幸的是，OA 患者不如没有 OA 的同龄人活跃。本研究的目的是确定有氧能力和疲劳度是否与髋 OA 女性的身体活动有关。我们对 36 名髋 OA 女性进行了横断面分析。我们通过 6 分钟步行测试预测 VO max 来评估有氧健身能力。我们使用跑步机测试评估疲劳度。最后，我们使用 UCLA 活动量表评估自我报告的身体活动，并使用加速度计量化每天的步数和活动强度。我们使用 Pearson 相关来确定关联。我们使用回归分析来确定疲劳度是否在有氧健身能力和身体活动之间的关联中起中介作用。平均而言，通过 UCLA 评分（10 分制中的 5.2±1.3 分），受试者的活动水平处于中等水平。有氧健身能力（R=0.582，p<.001）和疲劳度（R=0.516，p=.003）与 UCLA 评分显著相关。然而，有氧健身能力是 UCLA 评分以及久坐时间和轻体力活动时间的最佳预测指标。疲劳度不是有氧健身能力和 UCLA 评分之间的中介因素。有氧健身能力和疲劳度可能是 OA 患者身体活动的可改变障碍。未来的干预研究应检查改善有氧健身能力是否能提高身体活动或疲劳度。
