Mukhra Richa, Krishan Kewal, Kanchan Tanuj
Department of Anthropology (UGC Centre of Advanced Study), Panjab University, Sector-14, Chandigarh, India.
Department of Forensic Medicine and Toxicology, All India Institute of Medical Sciences Jodhpur, India.
Acta Biomed. 2020 Sep 7;91(3):e2020036. doi: 10.23750/abm.v91i3.10039.
The widespread outbreak of the novel SARS-CoV-2 has raised numerous questions about the origin and transmission of the virus. Knowledge about the mode of transmission as well as assessing the effectiveness of the preventive measures would aid in containing the outbreak of the coronavirus. Presently, respiratory droplets, physical contact and aerosols/air-borne have been reported as the modes of SARS-CoV-2 transmission of the virus. Besides, some of the other possible modes of transmission are being explored by the researchers, with some studies suggesting the viral spread through fecal-oral, conjunctival secretions, flatulence (farts), sexual and vertical transmission from mother to the fetus, and through asymptomatic carriers, etc. Aim: The primary objective was to review the present understanding and knowledge about the transmission of SARS-CoV-2 and also to suggest recommendations in containing and preventing the novel coronavirus.
A review of possible modes of transmission of the novel SARS-CoV-2 was conducted based on the reports and articles available in PubMed and ScienceDirect.com that were searched using keywords, 'transmission', 'modes of transmission', 'SARS-CoV-2', 'novel coronavirus', and 'COVID-19'. Articles referring to air-borne, conjunctiva, fecal-oral, maternal-fetal, flatulence (farts), and breast milk transmission were included, while the remaining were excluded.
The modes of transmission linked to SARS-CoV-2 were identified and the available literature on each of these is described in detail in view of the possibilities of viral transmission through various modes of transmission. The review provides updated and necessary information on the possible modes of transmission for the health care workers and the lay public under one umbrella that can also be considered during framing guidelines in order to prevent and control the viral spread.
新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的广泛爆发引发了关于该病毒起源和传播的诸多问题。了解传播方式以及评估预防措施的有效性将有助于控制冠状病毒的爆发。目前,呼吸道飞沫、身体接触和气溶胶/空气传播已被报道为SARS-CoV-2的传播方式。此外,研究人员正在探索其他一些可能的传播方式,一些研究表明病毒可通过粪口传播、结膜分泌物传播、肠胃胀气(放屁)传播、性传播以及从母亲到胎儿的垂直传播,还可通过无症状携带者等传播。目的:主要目标是回顾目前对SARS-CoV-2传播的理解和认识,并就控制和预防新型冠状病毒提出建议。
基于PubMed和ScienceDirect.com上可获取的报告和文章,使用关键词“传播”“传播方式”“SARS-CoV-2”“新型冠状病毒”和“COVID-19”进行搜索,对新型SARS-CoV-2可能的传播方式进行综述。纳入了涉及空气传播、结膜传播、粪口传播、母婴传播、肠胃胀气(放屁)传播和母乳传播的文章,其余文章则被排除。
确定了与SARS-CoV-2相关的传播方式,并鉴于病毒通过各种传播方式传播的可能性,详细描述了关于每种传播方式的现有文献。该综述为医护人员和普通公众提供了关于可能传播方式的最新且必要的信息,这些信息在制定指南时也可被考虑在内,以预防和控制病毒传播。