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药物纳米技术:哪些产品正在针对新冠病毒进行设计?

Pharmaceutical nanotechnology: which products are been designed against COVID-19?

作者信息

Cavalcanti Iago Dillion Lima, Cajubá de Britto Lira Nogueira Mariane

机构信息

Laboratório de Imunopatologia Keizo-Asami (LIKA), Universidade Federal de Pernambuco (UFPE), Av. Prof. Moraes Rego, 1235, Cidade Universitária, Recife, PE 50670-901 Brazil.

Laboratório de Nanotecnologia, Biotecnologia e Cultura de Células, Centro Acadêmico de Vitória (CAV), Universidade Federal de Pernambuco (UFPE), Rua Alto do Reservatório, s/n, Vitória de Santo Antão, 55608-680 PE Brazil.

出版信息

J Nanopart Res. 2020;22(9):276. doi: 10.1007/s11051-020-05010-6. Epub 2020 Sep 9.

DOI:10.1007/s11051-020-05010-6
PMID:32922162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7480001/
Abstract

The current pandemic COVID-19, caused by the SARS-CoV-2 virus, has been affecting thousands of people worldwide, promoting high numbers of deaths. With this, the world population is going through a process of changing habits, with social distance, improvement of hygiene techniques, to reduce the spread of the SARS-CoV-2 virus and, consequently, reduce the number of hospitalized people in serious condition, as well as the mortality rate. This scenario has been promoting a continuous search for researchers, in the most varied areas, for possible methods of prevention or cure. Specifically, in the field of pharmaceutical nanotechnology, a variety of products are being developed against SARS-CoV-2. Under these circumstances, we propose here an exposition of some of the nanotechnological products (nanoscale between 1 to 1000 nm) currently designed for the detection of the virus, for the prevention and treatment of COVID-19, in addition to equipment for personal protection. We believe that pharmaceutical nanotechnology will be a valuable tool in the disease from the development of products that guarantee our protection against the SARS-CoV-2 virus.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)病毒引起的当前新冠疫情,已在全球影响了数千人,导致大量死亡。由此,世界人口正在经历习惯改变的过程,包括保持社交距离、改进卫生技术,以减少SARS-CoV-2病毒的传播,从而减少重症住院人数以及死亡率。这种情况促使各个领域的研究人员不断寻找可能的预防或治疗方法。具体而言,在药物纳米技术领域,正在研发多种针对SARS-CoV-2的产品。在这种情况下,我们在此介绍一些目前设计用于检测该病毒、预防和治疗新冠的纳米技术产品(纳米尺度在1至1000纳米之间),以及个人防护设备。我们相信,药物纳米技术将成为开发保障我们免受SARS-CoV-2病毒侵害产品的宝贵工具,助力对抗这种疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/ef20b072309c/11051_2020_5010_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/fc5bd883dfaa/11051_2020_5010_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/eb8e5c202c0d/11051_2020_5010_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/ef20b072309c/11051_2020_5010_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/fc5bd883dfaa/11051_2020_5010_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/eb8e5c202c0d/11051_2020_5010_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1b/7480001/ef20b072309c/11051_2020_5010_Fig3_HTML.jpg

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