Moursy Safa, Gaballa Salem, Ahmed Ameenjamal, Hlaing Kyaw M, Patel Brijesh B
Internal Medicine, LewisGale Medical Center, Salem, USA.
Internal Medicine/Pulmonary and Critical Care, LewisGale Medical Center, Salem, USA.
Cureus. 2020 Aug 9;12(8):e9631. doi: 10.7759/cureus.9631.
Leukemia involves all organs and tissues of the body. Leukemic infiltration of the pericardium has been documented frequently at post-mortem examinations. Clinically, however, pericardial effusion with cardiac tamponade is rare, and only isolated case reports have been described. In all the reported cases, therapeutic pericardiocentesis was required for the relief of cardiac tamponade with the risk of bleeding since these patients often had deranged hemostasis. We are reporting a rare case of hemorrhagic pericardial effusion in chronic myeloid leukemia before starting the tyrosine kinase inhibitors. The patient required therapeutic pericardiocentesis and hydroxyurea treatment.
白血病累及身体的所有器官和组织。心包的白血病浸润在尸检中经常有记录。然而，临床上，伴有心脏压塞的心包积液很少见，仅有个别病例报告。在所有已报道的病例中，由于这些患者常伴有止血功能紊乱，为缓解心脏压塞需要进行治疗性心包穿刺，但存在出血风险。我们报告1例在开始使用酪氨酸激酶抑制剂之前发生的慢性髓性白血病出血性心包积液罕见病例。该患者需要进行治疗性心包穿刺及羟基脲治疗。
