Department of Gynecology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Department of Cardiac Surgery, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Jpn J Nurs Sci. 2021 Jan;18(1):e12344. doi: 10.1111/jjns.12344. Epub 2020 Sep 13.
Angong Niuhuang pill (ANP) is a traditional Chinese medicine (TCM) drug widely used for treating stroke. This study aimed to investigate the effect of ANP on respiratory nursing outcomes in chronic obstructive pulmonary disease (COPD) patients following cardiac surgery.
A total of 80 COPD patients following cardiac surgery were enrolled and randomized into the control group receiving routine postoperative nursing and ANP group additionally receiving ANP treatment for 3 days (n = 40 for both group). The frequency of back percussion, time of back percussion, amount of expectoration, arterial blood gas levels were compared between groups.
Compared to the control group, the ANP group had a significantly shorter daily mean time of back percussion at day 3 (p = .036) and day 7 (p = .014). The daily mean amount of expectoration was higher at day3 (p = .018) but lower at day 7 (p = .043) in the ANP group than in the control group. In addition, the ANP group had significantly higher hemoglobin saturation (SpO ) and partial pressure of oxygen (PaO ) but lower partial pressure of carbon dioxide (PaCO ) at both day 3 and day 7 than the control group (all p < .05). Furthermore, the time of postoperative aerosol inhalations (p = .041), pulmonary infection rate (p = .025) and postoperative hospital stay (p = .036) were significantly reduced in the ANP group. The ANP group had significantly lower TCM symptom scores at day 3 and day 7 after surgery.
These results suggested that ANP treatment can effectively promote the postoperative recovery and respiratory nursing outcomes in COPD patients following cardiac surgery.
安宫牛黄丸（ANP）是一种广泛用于治疗中风的中药（TCM）药物。本研究旨在探讨 ANP 对心脏手术后慢性阻塞性肺疾病（COPD）患者呼吸护理结局的影响。
共纳入 80 例心脏手术后的 COPD 患者，并随机分为对照组（接受常规术后护理）和 ANP 组（额外接受 ANP 治疗 3 天，每组 n = 40）。比较两组间叩背频率、叩背时间、排痰量、动脉血气水平。
与对照组相比，ANP 组第 3 天（p =.036）和第 7 天（p =.014）的每日平均叩背时间明显缩短。第 3 天（p =.018）和第 7 天（p =.043），ANP 组的每日平均排痰量较高，但第 7 天（p =.043）的每日平均排痰量较低。此外，ANP 组在第 3 天和第 7 天的血红蛋白饱和度（SpO ）和氧分压（PaO ）显著高于对照组，二氧化碳分压（PaCO ）显著低于对照组（均 p < .05）。此外，ANP 组术后雾化吸入时间（p =.041）、肺部感染率（p =.025）和术后住院时间（p =.036）明显缩短。第 3 天和第 7 天，ANP 组的中医症状评分明显降低。
这些结果表明，ANP 治疗可有效促进心脏手术后 COPD 患者的术后恢复和呼吸护理结局。
