应用剪切波弹性成像评估动脉性勃起功能障碍：一项可行性研究。

Evaluation of Arterial Erectile Dysfunction Using Shear Wave Elastography: A Feasibility Study.

机构信息

Department of Ultrasound, the First Affiliated Hospital of Anhui Medical University, Shushan District, Hefei, Anhui, China.

Department of Urology, the First Affiliated Hospital of Anhui Medical University, Shushan District, Hefei, Anhui, China.

出版信息

J Ultrasound Med. 2021 Jun;40(6):1209-1216. doi: 10.1002/jum.15502. Epub 2020 Sep 14.

DOI:10.1002/jum.15502

PMID:32926432

Abstract

OBJECTIVES

To explore the feasibility of shear wave elastography (SWE) in the evaluation of arterial erectile dysfunction (ED).

METHODS

From November 2018 to November 2019, 26 patients with arterial ED and 30 patients with non-vascular ED were prospectively included. SWE values of corpus cavernosum penis (CCP) and the flow velocity of cavernous artery for all patients in both before intracavernous injection (ICI) (flaccid state) and after ICI (erectile state) were measured. Performance of SWE value in assessing arterial ED was studied. Correlation between SWE value of CCP and the age of patients was also investigated.

RESULTS

ICI significantly reduced SWE values in both arterial and non-vascular group (from 19.57 ± 6.33 KPa to 12.17 ± 3.64 KPa in the first, and from 19.91 ± 6.69 KPa to 8.04 ± 3.13 KPa in the former, both P < .001). SWE values of CCP after ICI in arterial ED were significantly larger than that in non-vascular ED (P < .001). SWE values of CCP before ICI negatively correlated with age of patients in arterial ED (r = - 0.601, P < .001). With a cutoff value of 7.75 KPa, the area under curve, specificity, sensitivity, PPV, and NPV of SWE values of CCP after ICI in distinguishing arterial ED from non-vascular ED were 0.810, 63.3%, 96.2%, 96.2%, and 70%, respectively.

CONCLUSIONS

SWE was expected to be a potential technique for the noninvasive, simply operated, repeatable and quantitative evaluation of arterial ED.

摘要

目的

探讨剪切波弹性成像（SWE）在评估动脉性勃起功能障碍（ED）中的可行性。

方法

本研究为前瞻性研究，纳入 2018 年 11 月至 2019 年 11 月 26 例动脉性 ED 患者和 30 例非血管性 ED 患者。所有患者在阴茎海绵体（CCP）内注射前后（松弛状态和勃起状态）分别测量 SWE 值和海绵体动脉血流速度。研究 SWE 值评估动脉性 ED 的性能，并分析 CCP 的 SWE 值与患者年龄的相关性。

结果

ICI 显著降低了动脉性和非血管性 ED 患者的 SWE 值（前者从 19.57 ± 6.33 kPa 降至 12.17 ± 3.64 kPa，后者从 19.91 ± 6.69 kPa 降至 8.04 ± 3.13 kPa，均 P <.001）。动脉性 ED 患者 ICI 后的 CCP 的 SWE 值明显大于非血管性 ED 患者（P <.001）。动脉性 ED 患者 CCP 的 SWE 值与年龄呈负相关（r = -0.601，P <.001）。以 7.75 kPa 为截断值，CCP 内注射后 SWE 值鉴别动脉性 ED 和非血管性 ED 的曲线下面积、特异性、敏感性、阳性预测值和阴性预测值分别为 0.810、63.3%、96.2%、96.2%和 70%。