Mendelsohn Rebecca A, Taveras Anabelle N, Mazer Benjamin A, Clayton Lisa M
Florida Atlantic University Charles E. Schmidt College of Medicine, Department of Emergency Medicine, Boca Raton, Florida.
Clin Pract Cases Emerg Med. 2020 Aug;4(3):389-392. doi: 10.5811/cpcem.2020.4.46056.
Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of diabetes mellitus. Less prevalent is euglycemic DKA (eDKA)-DKA with serum glucose less than 200 mg/dL; however, it is increasing in frequency with the introduction of sodium glucose cotransporter 2 (SGLT-2) inhibitors for treatment of type 2 diabetes.
We report a case of SGLT-2 inhibitor-associated eDKA presenting with concurrent acute pericarditis.
Our case suggests that the cause of eDKA can be multifactorial when decreased oral intake occurs in the setting of an acute cause of physiologic stress.
Prompt recognition of eDKA in the emergency department may allow earlier diagnosis and treatment directed at one or more of its underlying causes.
糖尿病酮症酸中毒（DKA）是糖尿病一种潜在的危及生命的并发症。血糖正常的DKA（eDKA）——血清葡萄糖低于200mg/dL的DKA——相对少见；然而，随着用于治疗2型糖尿病的钠-葡萄糖协同转运蛋白2（SGLT-2）抑制剂的引入，其发生率正在增加。
我们报告1例与SGLT-2抑制剂相关的eDKA病例，该病例同时伴有急性心包炎。
我们的病例表明，当在急性生理应激情况下口服摄入量减少时，eDKA的病因可能是多因素的。
在急诊科及时识别eDKA可能有助于更早诊断并针对其一种或多种潜在病因进行治疗。
