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伊朗高血压前期和高血压的患病率及发病率(知晓率/控制率):克尔曼冠状动脉疾病危险因素研究2(KERCADRS)的结果

Prevalence and incidence of pre-hypertension and hypertension (awareness/control) in Iran: findings from Kerman coronary artery diseases risk factors study 2 (KERCADRS).

作者信息

Najafipour Hamid, Nasri Hamid Reza, Rostamzadeh Farzaneh, Amirzadeh Raheleh, Shadkam Mitra, Mirzazadeh Ali

机构信息

Physiology Research Center, Institute of Basic and Clinical Physiology Sciences, Kerman University of Medical Sciences, Kerman, Iran.

Department of Physiology and Pharmacology, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

J Hum Hypertens. 2022 May;36(5):461-472. doi: 10.1038/s41371-020-00392-5. Epub 2020 Sep 14.

Abstract

Hypertension (HTN) is an important cause of cardiovascular-related morbidity and mortality. The present study was conducted to investigate the prevalence and incidence rate of pre-HTN, diagnosed and undiagnosed HTN, as well as its control and associated factors in adult population in southeast Iran. In a randomized household survey, 9987 participants aged 15-80 years were recruited into the study. HTN was confirmed through examination or using antihypertensive drug(s). Pre-HTN and HTN were defined as 120-139/80-89 and ≥140/90 mmHg for systolic and diastolic BP, respectively. The prevalence of pre-HTN was 28.5%. The prevalence of HTN was 19.2% (13.9% diagnosed and 5.3% undiagnosed). HTN increased with age (from 4% in 15-24 to 67.8% in 75-80 years). Men had higher pre-HTN (35.6% vs. 23.4%) and undiagnosed HTN (7.5% vs. 3.8%) than women. Of those diagnosed, 46.5% had uncontrolled BP, in which, women had better conditions than men (45.6% vs. 47.4%). Obesity, positive family history of HTN, anxiety, and low physical activity were the most significant predictors of HTN. The prevalence of pre-HTN decreased but there was no change in the prevalence of HTN during the last 5 years. The 5-year incidence rate/100 person-years of pre-HTN and HTN was 6.6 and 3.7, respectively. Although there are some promising signs of reducing pre-HTN and slowing HTN rise, currently, almost one-fifth of the adult population suffers from HTN. Given the poor BP control in patients with diagnosed HTN, especially in men, alarms that more effective interventions and strategies are needed to reduce deleterious consequences of HTN.

摘要

高血压(HTN)是心血管相关发病和死亡的重要原因。本研究旨在调查伊朗东南部成年人群中高血压前期、已诊断和未诊断高血压的患病率、发病率及其控制情况和相关因素。在一项随机家庭调查中,招募了9987名年龄在15 - 80岁的参与者。通过检查或使用抗高血压药物确诊高血压。高血压前期和高血压分别定义为收缩压120 - 139/舒张压80 - 89 mmHg和收缩压≥140/舒张压≥90 mmHg。高血压前期的患病率为28.5%。高血压的患病率为19.2%(13.9%已诊断,5.3%未诊断)。高血压患病率随年龄增长而增加(从15 - 24岁的4%增至75 - 80岁的67.8%)。男性的高血压前期(35.6%对23.4%)和未诊断高血压(7.5%对3.8%)患病率高于女性。在已诊断的患者中,46.5%的血压未得到控制,其中女性情况优于男性(45.6%对47.4%)。肥胖、高血压家族史阳性、焦虑和低体力活动是高血压最显著的预测因素。在过去5年中,高血压前期患病率下降,但高血压患病率无变化。高血压前期和高血压的5年发病率/每100人年分别为6.6和3.7。尽管在降低高血压前期和减缓高血压上升方面有一些积极迹象,但目前近五分之一的成年人口患有高血压。鉴于已诊断高血压患者的血压控制不佳,尤其是男性,警示需要更有效的干预措施和策略来减少高血压的有害后果。

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