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伊朗南部科哈雷马队列研究中高血压前期和高血压的患病率及预测因素:一项针对 10663 人的基于人群的研究。

The prevalence and predictors of pre-hypertension and hypertension in Kherameh cohort study: a population based study on 10,663 persons in south of Iran.

机构信息

Colorectal Research Center, SUMS, Shiraz, Iran.

MSc Candidate of Epidemiology in Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

J Hum Hypertens. 2021 Mar;35(3):257-264. doi: 10.1038/s41371-020-0330-8. Epub 2020 Mar 17.

Abstract

Hypertension (HTN) is an important risk factor for cardiovascular disease (CVD) mortality and morbidity among Iranians. The present study aimed to estimate the prevalence of pre-HTN and HTN and some of its related factors in south of Iran. This cross-sectional survey was conducted on the data of the Persian cohort study in Kherameh. The participants consisted of 10,663 people aged 40-70 years. HTN was defined as either systolic/diastolic blood pressure (SBP/DBP) ≥140/90 mmHg or taking medications. Pre-HTN was defined as SBP = 120-139 mmHg and/or DBP = 80-89 mmHg. The logistic regression method was used to identify the factors associated with pre-HTN and HTN. The age-standardized prevalence rate (ASPR) of pre-HTN was 19.66% (95% CI: 19.45-19.86%) and 18.59% (95% CI: 18.36-18.83%) in males and females, respectively. Also, the ASPR of HTN was 21.44 (95% CI: 21.22-21.65%) in males and 33.53% (95% CI: 33.22-33.85%) in females. Male gender, old age, being unemployed, low education level, high body mass index (BMI), no smoking, diabetes, cerebro-cardiovascular disease, suffering from another chronic disease, family history of CVD, and negative family history of cancer and other chronic diseases were independently associated with pre-HTN (p < 0.05). All variables, except for gender, smoking, and family history of cancer, were significantly associated with HTN. Drug abuse was also correlated to HTN (p < 0.05). This study revealed the increased prevalence of HTN in rural and urban areas. Therefore, the health system needs to develop strategies to raise the accessibility of screening and diagnostic services.

摘要

高血压(HTN)是伊朗心血管疾病(CVD)死亡率和发病率的重要危险因素。本研究旨在估计伊朗南部地区的 Pre-HTN 和 HTN 的流行率及其一些相关因素。本横断面研究基于 Kherameh 的波斯队列研究的数据进行。参与者包括 10663 名年龄在 40-70 岁的人。HTN 定义为收缩压/舒张压(SBP/DBP)≥140/90mmHg 或服用药物。Pre-HTN 定义为 SBP=120-139mmHg 和/或 DBP=80-89mmHg。使用逻辑回归方法来确定与 Pre-HTN 和 HTN 相关的因素。男性和女性的 Pre-HTN 的年龄标准化患病率(ASPR)分别为 19.66%(95%CI:19.45-19.86%)和 18.59%(95%CI:18.36-18.83%)。此外,男性和女性的 HTN 的 ASPR 分别为 21.44%(95%CI:21.22-21.65%)和 33.53%(95%CI:33.22-33.85%)。男性性别、年龄较大、失业、教育水平低、高体重指数(BMI)、不吸烟、糖尿病、脑血管疾病、患有其他慢性疾病、CVD 家族史和癌症及其他慢性疾病的家族史与 Pre-HTN 独立相关(p<0.05)。除性别、吸烟和癌症家族史外,所有变量均与 HTN 显著相关。药物滥用也与 HTN 相关(p<0.05)。本研究显示 HTN 在农村和城市地区的患病率增加。因此,卫生系统需要制定策略来提高筛查和诊断服务的可及性。

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