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Artificial intelligence, drug repurposing and peer review.

作者信息

Levin Jeremy M, Oprea Tudor I, Davidovich Sagie, Clozel Thomas, Overington John P, Vanhaelen Quentin, Cantor Charles R, Bischof Evelyne, Zhavoronkov Alex

机构信息

Ovid Therapeutics, Inc, New York, NY, USA.

Biotechnology Innovation Organization (BIO), Washington, DC, USA.

出版信息

Nat Biotechnol. 2020 Oct;38(10):1127-1131. doi: 10.1038/s41587-020-0686-x.

DOI:10.1038/s41587-020-0686-x
PMID:32929264
Abstract
摘要

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[A pilot study of hydroxychloroquine in treatment of patients with moderate COVID-19].羟氯喹治疗中度新型冠状病毒肺炎患者的一项试点研究
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):215-219. doi: 10.3785/j.issn.1008-9292.2020.03.03.
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BioBERT: a pre-trained biomedical language representation model for biomedical text mining.BioBERT:一种用于生物医学文本挖掘的预训练生物医学语言表示模型。
Bioinformatics. 2020 Feb 15;36(4):1234-1240. doi: 10.1093/bioinformatics/btz682.
2010-2022 年期间欧盟孤儿药批准的趋势。
Orphanet J Rare Dis. 2024 Feb 27;19(1):91. doi: 10.1186/s13023-024-03095-z.
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Unraveling viral drug targets: a deep learning-based approach for the identification of potential binding sites.解析病毒药物靶点:基于深度学习的潜在结合位点鉴定方法。
Brief Bioinform. 2023 Nov 22;25(1). doi: 10.1093/bib/bbad459.
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A review of SARS-CoV-2 drug repurposing: databases and machine learning models.新型冠状病毒2型药物重新利用综述:数据库与机器学习模型
Front Pharmacol. 2023 Aug 4;14:1182465. doi: 10.3389/fphar.2023.1182465. eCollection 2023.
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Drug repurposing for reducing the risk of cataract extraction in patients with diabetes mellitus: integration of artificial intelligence-based drug prediction and clinical corroboration.药物再利用以降低糖尿病患者白内障摘除风险:基于人工智能的药物预测与临床验证的整合
Front Pharmacol. 2023 May 18;14:1181711. doi: 10.3389/fphar.2023.1181711. eCollection 2023.
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Emerging Treatment Approaches for COVID-19 Infection: A Critical Review.新型冠状病毒肺炎感染的新兴治疗方法:批判性综述
Curr Mol Med. 2024;24(4):435-448. doi: 10.2174/1566524023666230417112543.
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Intelligent De Novo Design of Novel Antimicrobial Peptides against Antibiotic-Resistant Bacteria Strains.智能从头设计新型抗菌肽对抗抗生素耐药菌。
Int J Mol Sci. 2023 Apr 5;24(7):6788. doi: 10.3390/ijms24076788.
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Heliyon. 2023 Mar;9(3):e14115. doi: 10.1016/j.heliyon.2023.e14115. Epub 2023 Mar 6.
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Nucleic Acids Res. 2023 Jan 6;51(D1):D1276-D1287. doi: 10.1093/nar/gkac1085.