Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Benha University, Toukh, 13736, Egypt.
Department of Parasitology and Animal Diseases, National Research Center, Dokki, Giza, Egypt.
Trop Anim Health Prod. 2020 Nov;52(6):3381-3385. doi: 10.1007/s11250-020-02370-y. Epub 2020 Sep 14.
Neospora caninum is an obligate intercellular protozoan parasite and considered one of the abortive pathogens in a wide range of ruminants. The present study aimed to investigate the antibodies against N. caninum in camels from three governorates in Egypt to understand the epidemiology of neosporosis and its associated abortion. The study was carried out on 282 camels using commercial enzyme-linked immunosorbent assay (ELISA) kit. The obtained results confirmed the presence of anti-Neospora caninum antibodies in 31 out of 282 camels. Moreover, no significant difference in seroprevalence was observed between different localities under the study and between males and females. On contrary, the number of seropositive camels was increased significantly in adult camels of 8-11 years old (OR = 9.1, 95% CI: 1.1-73.1), during the autumn (OR = 2.3, 95% CI: 0.79-7.1) and mainly in females with history of abortion (OR = 2.8, 95% CI: 1.2-6.5) or in camels raised with dogs (OR = 2.8, 95% CI: 1.1-7.08). The presence of antibodies against N. caninum in camels from Egypt increases the demand for further studies to determine its epidemiological role as a cause of abortion and reduce its economic impacts on camel's industry.
刚地弓形虫是一种专性细胞内原生动物寄生虫，被认为是广泛反刍动物中流产的病原体之一。本研究旨在调查埃及三个省骆驼中的抗刚地弓形虫抗体，以了解新孢子虫病及其相关流产的流行病学。该研究使用商业酶联免疫吸附试验（ELISA）试剂盒对 282 只骆驼进行了研究。结果证实，在 282 只骆驼中有 31 只存在抗刚地弓形虫抗体。此外，在所研究的不同地区以及雄性和雌性之间，血清阳性率没有显著差异。相反，在 8-11 岁的成年骆驼中，血清阳性的骆驼数量明显增加（OR=9.1，95%CI：1.1-73.1），在秋季（OR=2.3，95%CI：0.79-7.1），主要是有流产史的雌性骆驼（OR=2.8，95%CI：1.2-6.5）或与狗一起饲养的骆驼（OR=2.8，95%CI：1.1-7.08）。埃及骆驼中存在抗刚地弓形虫抗体，增加了进一步研究的需求，以确定其作为流产原因的流行病学作用，并降低其对骆驼产业的经济影响。
