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经皮肾镜取石术在脊髓损伤患者中的应用:是否所有这些患者都应自动被分配 Guy 结石评分 4 分?

Percutaneous nephrolithotomy in patients with spinal cord injury: should all these patients be automatically assigned a Guy's stone score of 4?

机构信息

Division of Urology, University of Sao Paulo Medical School, Av. Vereador Jose Diniz, 3300, conj. 208, Sao Paulo, SP, 04604-006, Brazil.

Division of Urology, Hospital Brigadeiro, Sao Paulo, SP, Brazil.

出版信息

World J Urol. 2021 Jun;39(6):2129-2134. doi: 10.1007/s00345-020-03443-1. Epub 2020 Sep 15.

Abstract

PURPOSE

To assess the complication and stone-free rates of PCNL in patients with spinal cord injury (SCI) and to evaluate whether this population should be assigned a Guy's stone score (GSS) of 4.

METHODS

A case-control study was conducted, and electronic charts were reviewed to search for patients with SCI, bladder dysfunction, and kidney stones who had undergone PCNL. Control cases were randomly selected from among patients with complete staghorn calculus (GSS = 4).

RESULTS

One hundred and seventeen patients were included. Patients with SCI had a significant shorter operative time (119 vs. 141 min; p = 0.018). There were no significant differences between the groups in terms of the patients' position, number of renal tracts, bleeding or transfusion rate; however, there was a significantly higher complication rate (23.1% vs. 7.8%; p = 0.009) and a longer hospital stay (5.8 vs. 3.1 days; p = 0.002) among patients with SCI. With regards to the stone-free rate in patients with different grades of GSS patients with SCI who had a GSS of 1 had a stone-free rate of 85.7%, while those with a GSS of 2, 3, or 4 had 50%, 50%, and 31.5%, respectively (p = 0.024). Only patients with a GSS of 4 in the SCI group had outcomes that were similar to those of control patients (31.5% vs. 31.6%).

CONCLUSION

Patients with SCI should not be automatically assigned GSS 4. Stone-free rate is related to stone burden in these patients, although they do show a higher complication rate and a longer hospital stay than non-neurological patients.

摘要

目的

评估脊髓损伤(SCI)患者行 PCNL 的并发症和结石清除率,并评估该人群是否应被赋予 Guy 结石评分(GSS)4 分。

方法

进行了一项病例对照研究,回顾电子病历以搜索患有 SCI、膀胱功能障碍和肾结石并接受 PCNL 的患者。对照组病例随机选自完全鹿角结石患者(GSS=4 分)。

结果

共纳入 117 例患者。SCI 组的手术时间显著更短(119 分钟 vs. 141 分钟;p=0.018)。两组患者的体位、肾通道数量、出血或输血率无显著差异;然而,SCI 组的并发症发生率(23.1% vs. 7.8%;p=0.009)和住院时间(5.8 天 vs. 3.1 天;p=0.002)明显更高。根据不同 GSS 分级的 SCI 患者的结石清除率,GSS 为 1 的 SCI 患者结石清除率为 85.7%,GSS 为 2、3 或 4 的患者结石清除率分别为 50%、50%和 31.5%(p=0.024)。只有 SCI 组中 GSS 为 4 的患者的结果与对照组患者相似(31.5% vs. 31.6%)。

结论

不应自动将 SCI 患者赋予 GSS 4 分。尽管 SCI 患者的并发症发生率和住院时间高于非神经患者,但结石清除率与结石负荷有关。

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