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经皮脊柱内窥镜与传统开放手术治疗腰椎间盘突出症的临床疗效和安全性的系统评价和荟萃分析。

Clinical Efficacy and Safety of Percutaneous Spinal Endoscopy versus Traditional Open Surgery for Lumbar Disc Herniation: Systematic Review and Meta-Analysis.

机构信息

Department of Orthopedics, 14F Yinzhou People's Hospital, No. 251 Baizhang East Road, Yinzhou District, Ningbo, Zhejiang Province, China.

The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang Province, China.

出版信息

J Healthc Eng. 2022 Mar 16;2022:6033989. doi: 10.1155/2022/6033989. eCollection 2022.

Abstract

OBJECTIVE

Systematic analysis of the incidence of percutaneous spinal endoscopic technique and traditional open surgery for lumbar disc herniation.

METHODS

A randomized controlled trial (RCT) and cohort study on complications related to traditional open surgery was searched on the MEDLINE, Cochrane Library, PubMed, Web of Science, Chinese journal full-text database (CNKI), Wanfang, and Embase database. Language is not limited. The quality of each study was evaluated, various complications were compiled into electronic baseline tables, and the data from these studies were available. Meta-analysis and synthesis were performed with the RevMan 5.3 software to evaluate the statistical significance of both surgical techniques in terms of various complications.

RESULTS

12 studies were eventually included, and a total of 2,797 patients were included in the analysis. Meta-analysis results showed that there was no statistical difference in postoperative paresthesia between percutaneous spinal endoscopy and traditional open surgery (OR = 1.17, 95% CI (0.82, 1.66),  = 0.38,  = 0%,  = 0.88), direct nerve root damage (OR = 0.79, 95% CI (0.58, 1.07),  = 0.13,  = 73%,  = 1.52), and intraoperative hemorrhage and hematoma formation (OR = 1.00, 95% CI (0.67, 1.48),  = 0.99,  = 0%,  = 0.02), but there was a statistical difference in disc recurrence (OR = 2.24, 95% CI (1.56, 3.21),  < 0.0001,  = 81%,  = 4.39).

CONCLUSION

Compared with the traditional open surgical treatment of lumbar disc herniation, percutaneous spinal endoscopic technology has obvious advantages in reducing nerve root injury, dural injury, and surgical area wound complications, but it is limited to preventing the technical characteristics of the surgical site, which is worse than that of open surgery.

摘要

目的

系统分析经皮脊柱内窥镜技术与传统开放手术治疗腰椎间盘突出症的发病率。

方法

检索 MEDLINE、Cochrane 图书馆、PubMed、Web of Science、中国期刊全文数据库(CNKI)、万方和 Embase 数据库中与传统开放手术相关并发症的随机对照试验(RCT)和队列研究。语言不受限制。评估每个研究的质量,将各种并发症编制成电子基线表,并获取这些研究的数据。使用 RevMan 5.3 软件进行荟萃分析和综合,以评估两种手术技术在各种并发症方面的统计学意义。

结果

最终纳入 12 项研究,共纳入 2797 例患者进行分析。荟萃分析结果显示,经皮脊柱内窥镜与传统开放手术治疗术后感觉异常(OR=1.17,95%CI(0.82,1.66))、直接神经根损伤(OR=0.79,95%CI(0.58,1.07))、术中出血和血肿形成(OR=1.00,95%CI(0.67,1.48))差异均无统计学意义(均 P>0.05),但椎间盘复发(OR=2.24,95%CI(1.56,3.21))差异有统计学意义(P<0.0001)。

结论

与传统开放手术治疗腰椎间盘突出症相比,经皮脊柱内窥镜技术在减少神经根损伤、硬脊膜损伤和手术区域伤口并发症方面具有明显优势,但受手术部位技术特点的限制,其效果逊于开放手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dee/8942646/cc046147e3b5/JHE2022-6033989.001.jpg

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