From the Division of Pediatrics, University Hospital, University of Sao Paulo - SP, Sao Paulo, Brazil.
Emergency Department, Hospital Israelita Albert Einstein, Sao Paulo - SP, Brazil.
Pediatr Infect Dis J. 2020 Oct;39(10):e321-e324. doi: 10.1097/INF.0000000000002834.
Although first considered a benign infection, recent studies have disclosed severe and potentially lethal inflammatory manifestations of COVID-19 in children. We report the case of a 4-year-old child with a post-infectious multisystem inflammatory syndrome associated with COVID-19, with a Kawasaki-like shock and prominent neurologic features, for whom a cytokine storm and reduced brain-derived neurotrophic factor were well documented.
尽管最初被认为是一种良性感染,但最近的研究揭示了 COVID-19 在儿童中存在严重且可能致命的炎症表现。我们报告了一例与 COVID-19 相关的儿童感染后多系统炎症综合征病例,该病例表现为川崎样休克和突出的神经特征,其细胞因子风暴和脑源性神经营养因子减少得到了很好的记录。