Baker Tamara, Naylor Heather, MacNeil Bryanne, MacKinnon Martin
Department of Pharmacy, Nova Scotia Health Authority (Central Zone), QEII Health Sciences Centre, Halifax, NS B3K 4N1, Canada.
Department of Pharmacy, Horizon Health Network, Saint John Regional Hospital, Saint John, NB E2L 4L4, Canada.
Pharmacy (Basel). 2020 Sep 14;8(3):171. doi: 10.3390/pharmacy8030171.
Chronic kidney disease mineral and bone disorder (CKD-MBD) is a common complication in end-stage renal disease (ESRD). To improve prescribing consistency and patient outcomes, a patient-centered, pharmacist-dietician-led approach to managing CKD-MBD was developed. The purpose of this study was to evaluate if the new approach impacted serum markers of CKD-MBD and medication burden, and to evaluate patient satisfaction. A single-arm, pre-post, mixed-methods study was conducted. Serum markers of CKD-MBD and medication data were collected pre- and post-intervention, and a patient survey administered post-intervention. Focus groups were conducted, transcribed, and analyzed thematically. No statistically significant differences in serum markers of CKD-MBD or medication burden were found. Eighty-seven percent of patients were satisfied with their care, however, 31% were very dissatisfied with medical explanations provided to them and 48% felt their allotted time with healthcare professionals was too short. Four major themes identified from focus groups included lack of privacy, knowledge and perceptions of blood work rounds, issues with taking phosphate binders, and areas for increased patient education. Patients would prefer more information regarding their blood work results and more time with the healthcare team. Areas for expanded education include renal diet, phosphate binders, and consequences of abnormal bloodwork.
慢性肾脏病矿物质和骨异常(CKD-MBD)是终末期肾病(ESRD)的常见并发症。为提高处方的一致性和患者治疗效果,制定了一种以患者为中心、由药剂师-营养师主导的CKD-MBD管理方法。本研究的目的是评估这种新方法是否会影响CKD-MBD的血清标志物和药物负担,并评估患者满意度。开展了一项单组前后对照的混合方法研究。在干预前后收集CKD-MBD的血清标志物和用药数据,并在干预后进行患者调查。进行了焦点小组讨论,对讨论内容进行转录并进行主题分析。未发现CKD-MBD血清标志物或药物负担有统计学显著差异。87%的患者对其治疗感到满意,然而,31%的患者对提供给他们的医学解释非常不满意,48%的患者觉得他们与医护人员的预约时间太短。焦点小组确定的四个主要主题包括缺乏隐私、对血液检查查房的了解和认知、服用磷结合剂的问题以及加强患者教育的领域。患者希望获得更多有关其血液检查结果的信息,并希望有更多时间与医护团队交流。需要扩大教育的领域包括肾脏饮食、磷结合剂以及血液检查异常的后果。