Department of Psychiatry, Weill Cornell Medicine, New York, NY, USA.
Department of Psychology, University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
J Behav Med. 2021 Feb;44(1):131-137. doi: 10.1007/s10865-020-00175-w. Epub 2020 Sep 16.
Little is known about contributors to the psychosocial impact of uveal melanoma, a rare cancer. Predictors and outcomes of benefit finding, a potentially favorable outcome, were investigated. Adults (n = 107) completed assessments prior to diagnosis of uveal melanoma and one week, three months and 12 months after diagnosis. Path analyses with the full information maximum likelihood estimation method were conducted. Objective disease impact on vision did not predict benefit finding (p > .05). Approach-oriented coping prior to diagnosis and one week later significantly predicted greater benefit finding 12 months later (p < .01). Avoidance-oriented coping at three months moderated the concurrent relationship of benefit finding and positive affect at 12 months (p < .001). This first study of predictors of benefit finding in uveal melanoma patients suggests that greater approach-oriented coping prospectively predicts higher benefit finding. Further, avoidance may condition the association of benefit finding with psychosocial outcomes.
人们对葡萄膜黑色素瘤（一种罕见的癌症）的心理社会影响的贡献知之甚少。本研究调查了获益发现（一种潜在有利的结果）的预测因素和结果。107 名成年人在诊断出葡萄膜黑色素瘤之前以及诊断后一周、三个月和十二个月完成了评估。采用全信息最大似然估计法进行路径分析。客观疾病对视力的影响并不能预测获益发现（p>.05）。诊断前和一周后的目标导向应对显著预测 12 个月后更大的获益发现（p<.01）。三个月时的回避导向应对调节了 12 个月时获益发现与积极情绪的并发关系（p<.001）。这是第一项关于葡萄膜黑色素瘤患者获益发现预测因素的研究，表明更大的目标导向应对可以预测更高的获益发现。此外，回避可能会影响获益发现与心理社会结果的关联。
