某些吡咯衍生物的合成及其生物活性。I.
Synthesis and biological activity of some pyrrole derivatives. I.
作者信息
Cocco M T, Congiu C, Maccioni A, Plumitallo A, Schivo M L, Palmieri G
机构信息
Istituto di Chimica Farmaceutica, Tossicologica ed Applicata Università di Cagliari, Italy.
出版信息
Farmaco Sci. 1988 Jan;43(1):103-12.
PMID:3294040
Abstract
The synthesis of some 5-substituted 2-amino-3-cyano (and 3-carboethoxy)pyrroles is described starting from the cyano- and carboethoxyacetomidines and the alpha-halogeno ketones. The compounds tested in vitro as antimicrobial agents did not show any significative activity.
摘要
描述了从氰基乙脒和乙氧羰基乙脒以及α-卤代酮出发合成一些5-取代的2-氨基-3-氰基（和3-乙氧羰基）吡咯的方法。作为抗菌剂进行体外测试的这些化合物未显示出任何显著活性。
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