部落管理下的基层医疗中的精准医疗观。
Perspectives on Precision Medicine in a Tribally Managed Primary Care Setting.
机构信息
Southcentral Foundation, Anchorage, Alaska, USA.
Department of Anthropology, University of Oklahoma, Norman, Oklahoma, USA.
出版信息
AJOB Empir Bioeth. 2020 Oct-Dec;11(4):246-256. doi: 10.1080/23294515.2020.1817172. Epub 2020 Sep 17.
BACKGROUND
Precision medicine (PM) research and clinical application is moving forward at a rapid pace. To ensure ethical inclusion of all populations in PM, in-depth understanding of diverse communities' views of PM research and PM implementation is necessary.
METHODS
Semi-structured interviews were conducted to explore perspectives on PM in a tribally managed healthcare organization. Thematic analysis was used to analyze data from 46 interviews.
RESULTS
Participants described gains in diagnostic efficiency, risk identification for preventable disease, and the advancement of population-specific biomedical research as key benefits of PM. Concerns expressed related to privacy risks associated with data-sharing, overpromising on PM, and managing patient expectations related to PM. Stakeholders encouraged PM implementation to be preceded by health education activities that leverage a range of communication strategies.
CONCLUSION
Perspectives described in this study may aid in and should be considered prior to implementation of PM in this and other healthcare systems, especially those serving diverse populations.
背景
精准医学（PM）的研究和临床应用正在迅速推进。为确保所有人群都能在 PM 中得到公平包容，深入了解不同社区对 PM 研究和 PM 实施的看法是必要的。
方法
采用半结构式访谈的方式，在一个部落管理的医疗保健组织中探讨对 PM 的看法。采用主题分析法对 46 次访谈的数据进行分析。
结果
参与者描述了 PM 在提高诊断效率、识别可预防疾病的风险，以及推进特定人群的生物医学研究方面的好处。他们还表达了对数据共享相关隐私风险、PM 的过度承诺以及管理 PM 相关患者期望的担忧。利益相关者鼓励在实施 PM 之前，先开展健康教育活动，利用多种沟通策略。
结论
本研究中描述的观点可能有助于并应在本研究和其他医疗保健系统中实施 PM 之前进行考虑，特别是在为不同人群服务的系统中。
Zotero 插件