Truedson Petra, Ott Michael, Bernberg Evelina, Werneke Ursula
ST-läkare i psykiatri, Sunderby sjukhus, Luleå.
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Lakartidningen. 2020 Sep 15;117:F3LI.
Neuroleptic malignant syndrome and serotonin syndrome are two conditions that can occur with psychotropic medications. Although both states are associated with psychiatric care they can also occur in somatic settings. The clinical pictures are complex with many different symptoms of varying severity. Both diagnoses are therefore easy to miss. Opinions remain divided on how to treat both states pharmacologically. The aim of this article is to increase the understanding and awareness of these potentially life-threatening conditions, which arise from treatment with dopaminergic or serotonergic substances.
抗精神病药恶性综合征和血清素综合征是两种可能与精神药物相关的病症。虽然这两种状态都与精神科护理有关，但它们也可能出现在躯体疾病背景中。临床表现复杂，有许多严重程度不同的症状。因此，这两种诊断都很容易被漏诊。关于如何从药理学角度治疗这两种状态，目前仍存在分歧。本文的目的是增进对这些由多巴胺能或血清素能物质治疗引起的、可能危及生命的病症的理解和认识。
