Schuett Timo, Kimmig Julian, Zechel Stefan, Schubert Ulrich S
Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich Schiller University Jena, Humboldtstr. 10, 07743 Jena, Germany.
Jena Center of Soft Matter (JCSM), Friedrich Schiller University Jena, Philosophenweg 7, 07743 Jena, Germany.
Polymers (Basel). 2020 Sep 15;12(9):2095. doi: 10.3390/polym12092095.
The automated dialysis of polymers in synthetic robots is described as a first approach for the purification of polymers using an automated protocol. For this purpose, a dialysis apparatus was installed within a synthesis robot. Therein, the polymer solution could be transferred automatically into the dialysis tube. Afterwards, a permanent running dialysis could be started, enabling the removal of residual monomer. Purification efficiency was studied using chromatography and NMR spectroscopy, showing that the automated dialysis requires less solvent and is faster compared to the classical manual approach.
合成机器人中聚合物的自动透析被描述为使用自动协议纯化聚合物的第一种方法。为此，在合成机器人内安装了透析装置。在该装置中，聚合物溶液可自动转移至透析管中。之后，可开始持续进行的透析，以去除残留单体。使用色谱法和核磁共振光谱法研究了纯化效率，结果表明与传统手动方法相比，自动透析所需溶剂更少且速度更快。
