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使用专家标记的听力学数据和常见听力学功能参数进行自动听力学分类的敏感性和特异性。

Sensitivity and specificity of automatic audiological classification using expert-labelled audiological data and Common Audiological Functional Parameters.

机构信息

Medizinische Physik, Universität Oldenburg, Oldenburg, Germany.

Cluster of Excellence Hearing4all, Oldenburg, Germany.

出版信息

Int J Audiol. 2021 Jan;60(1):16-26. doi: 10.1080/14992027.2020.1817581. Epub 2020 Sep 18.

DOI:10.1080/14992027.2020.1817581
PMID:32945703
Abstract

OBJECTIVE

As a step towards the development of an audiological diagnostic supporting tool employing machine learning methods, this article aims at evaluating the classification performance of different audiological measures as well as Common Audiological Functional Parameters (CAFPAs). CAFPAs are designed to integrate different clinical databases and provide abstract representations of measures.

DESIGN

Classification and evaluation of classification performance in terms of sensitivity and specificity are performed on a data set from a previous study, where statistical models of diagnostic cases were estimated from expert-labelled data.

STUDY SAMPLE

The data set contains 287 cases.

RESULTS

The classification performance in clinically relevant comparison sets of two competing categories was analysed for audiological measures and CAFPAs. It was found that for different audiological diagnostic questions a combination of measures using different weights of the parameters is useful. A set of four to six measures was already sufficient to achieve maximum classification performance which indicates that the measures contain redundant information.

CONCLUSIONS

The current set of CAFPAs was confirmed to yield in most cases approximately the same classification performance as the respective optimum set of audiological measures. Overall, the concept of CAFPAs as compact, abstract representation of auditory deficiencies is confirmed.

摘要

目的

作为开发采用机器学习方法的听力诊断支持工具的一步,本文旨在评估不同听力测量值以及常见听力功能参数(CAFPAs)的分类性能。CAFPAs 旨在整合不同的临床数据库,并提供测量值的抽象表示。

设计

在之前研究的数据集上进行分类,并根据灵敏度和特异性评估分类性能,其中从专家标记的数据中估计诊断病例的统计模型。

研究样本

数据集包含 287 例。

结果

分析了用于听力测量值和 CAFPAs 的两种竞争类别在临床相关比较集中的分类性能。结果发现,对于不同的听力诊断问题,使用不同参数权重的组合测量值是有用的。一组四到六个测量值已经足以达到最大的分类性能,这表明这些测量值包含冗余信息。

结论

当前的 CAFPAs 集被证实,在大多数情况下,其分类性能与各自最佳的听力测量值集大致相同。总体而言,CAFPAs 作为听觉缺陷的紧凑、抽象表示的概念得到了证实。

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