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通过实施多学科筛查流程降低儿科非特发性脊柱侧凸的死亡率。

Reduction in mortality in pediatric non-idiopathic scoliosis by implementing a multidisciplinary screening process.

机构信息

Baylor College of Medicine, Houston, TX, USA.

Texas Children's Hospital, Houston, TX, USA.

出版信息

Spine Deform. 2021 Jan;9(1):119-124. doi: 10.1007/s43390-020-00202-5. Epub 2020 Sep 18.

Abstract

STUDY DESIGN

Retrospective comparative study.

OBJECTIVES

To compare complications before and after implementation of the Multi-D screening protocol in complex pediatric patients undergoing spinal instrumentation for non-idiopathic scoliosis. Pediatric patients undergoing surgery for non-idiopathic scoliosis experience significantly more complications than those with idiopathic scoliosis. Operating on these patients can lead to serious complications including death. Recent reports have demonstrated the benefits of establishing a multidisciplinary-based system to reduce complications in adult spinal deformity during the perioperative period. However, there are limited studies examining these benefits in a complex pediatric spine population.

METHODS

This was a retrospective review of all cases involving spinal instrumentation at our institution for 2 years before and after the initiation of our Neuromuscular Spine Surgery Care Plan in July 2014. Study sample was n = 129 cases (107 patients) prior to the initiation of the process and n = 122 cases (109 patients) thereafter. Primary outcome measures included: mortality at 30 days and 1 year; post-operative neurologic deficit, and surgical site infections (SSI). Secondary outcome measures included: instrument failure in 1 year; readmission in 30 days; return to OR in 90 days.

RESULTS

The study populations were matched by age and gender. Patients passing the Multi-D conference had higher BMI. Implementation of the Multi-D conference reduced mortality at 30 days (2 vs 0, p = 0.17) and at 1 year (4 vs 0, p = 0.04), as well as reduced post-operative neurologic deficit (2 vs 0, p = 0.17). The rate of SSI remained unchanged. All other secondary outcome measures also remained unchanged.

CONCLUSIONS

Implementation of a Multi-D conference led to a significant reduction in mortality at 1 year, and is an important safety process to reduce serious complications after non-idiopathic scoliosis surgery.

LEVEL OF EVIDENCE

Level III.

摘要

研究设计

回顾性对比研究。

目的

比较在为非特发性脊柱侧凸行脊柱器械固定的复杂儿科患者中实施多学科筛查方案前后的并发症。与特发性脊柱侧凸患者相比,接受非特发性脊柱侧凸手术的儿科患者经历了更多的并发症。对这些患者进行手术可能导致严重的并发症,包括死亡。最近的报告表明,建立一个多学科为基础的系统可以在成人脊柱畸形围手术期减少并发症,这是有益的。然而,在复杂的儿科脊柱人群中,研究这些益处的研究有限。

方法

这是我们机构 2014 年 7 月启动神经肌肉脊柱手术护理计划前后 2 年所有脊柱器械治疗病例的回顾性研究。研究样本在该过程启动前为 n=129 例(107 例患者),此后为 n=122 例(109 例患者)。主要观察指标包括:30 天和 1 年的死亡率;术后神经功能缺损和手术部位感染(SSI)。次要观察指标包括:1 年内器械失效;30 天内再入院;90 天内返回手术室。

结果

研究人群在年龄和性别上相匹配。通过多学科会议的患者 BMI 较高。多学科会议的实施降低了 30 天(2 比 0,p=0.17)和 1 年(4 比 0,p=0.04)的死亡率,以及术后神经功能缺损(2 比 0,p=0.17)。SSI 的发生率保持不变。所有其他次要观察指标也保持不变。

结论

多学科会议的实施显著降低了 1 年的死亡率,是减少非特发性脊柱侧凸手术后严重并发症的重要安全措施。

证据水平

III 级。

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