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COVID-19 血清学检测的最新进展。

Update on serologic testing in COVID-19.

机构信息

Department and Clinic of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, Poland.

Department of Pathology, Wroclaw Medical University, Poland.

出版信息

Clin Chim Acta. 2020 Nov;510:746-750. doi: 10.1016/j.cca.2020.09.015. Epub 2020 Sep 15.

Abstract

Serologic tests are one of the available diagnostic tools in COVID-19. Growing literature highlights their role in the clinical management of the disease. Unfortunately, due to the limited availability of commercial tests and the lack of reliable trials establishing the sensitivity and specificity of the diagnostic method, the clinical application of the test needs to be precisely determined. In this paper, we discuss the utility of anti-SARS-CoV-2 serology testing in a clinical setting and propose diagnostic algorithms that include serological tests in patients with confirmed or suspected COVID-19.

摘要

血清学检测是 COVID-19 可用的诊断工具之一。越来越多的文献强调了它们在疾病临床管理中的作用。不幸的是,由于商业检测的可用性有限,并且缺乏可靠的试验来确定诊断方法的灵敏度和特异性,因此需要精确确定检测的临床应用。本文讨论了抗 SARS-CoV-2 血清学检测在临床环境中的实用性,并提出了包括确诊或疑似 COVID-19 患者血清学检测的诊断算法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7377/7491380/f46d576c896e/gr1_lrg.jpg

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