Grau-Bartual Sandra, Al-Jumaily Ahmed M
Institute of Biomedical Technologies, Auckland University of Technology, Auckland, New Zealand.
Institute of Biomedical Technologies, Auckland University of Technology, Auckland, New Zealand.
J Biomech. 2020 Nov 9;112:110037. doi: 10.1016/j.jbiomech.2020.110037. Epub 2020 Sep 10.
Continuous positive airway pressure is the most effective long-term treatment for obstructive sleep apnoea, which is a sleeping disorder characterized by pauses in breathing during sleep. It introduces pressurized atmospheric air into the respiratory system in order to maintain open airways without blockage. Some continuous positive airway pressure devices incorporate a convective heat transfer humidifier to overcome dryness. However, many side effects, including the unacceptable excess of water droplets in the air supply line, have been reported and improvements are essential for better patient's comfort and acceptance of the therapy. The excess of water droplets is attributed to the qualitative rather than the quantitative approach of determining the rise in temperature and humidity of the inspired air. Therefore, a human upper airway mathematical model is developed to predict the heat and water transfer variation between normal breathing and continuous positive airway pressure conditions and determine the optimal input temperature and relative humidity in the continuous positive airway pressure humidifier.
持续气道正压通气是阻塞性睡眠呼吸暂停最有效的长期治疗方法，阻塞性睡眠呼吸暂停是一种睡眠障碍，其特征是睡眠期间呼吸暂停。它将加压的大气引入呼吸系统，以保持气道畅通无阻。一些持续气道正压通气设备配备了对流热传递加湿器，以克服干燥问题。然而，已经报告了许多副作用，包括供气管道中不可接受的过多水滴，为了提高患者的舒适度和对治疗的接受度，改进至关重要。过多的水滴归因于确定吸入空气温度和湿度升高的定性而非定量方法。因此，开发了一种人体上呼吸道数学模型，以预测正常呼吸和持续气道正压通气条件下的热和水传递变化，并确定持续气道正压通气加湿器的最佳输入温度和相对湿度。
