Sleep Disorders Center, Department of Neurology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.
Department of Epidemiology, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA.
Sleep Med. 2021 Jan;77:304-306. doi: 10.1016/j.sleep.2020.08.025. Epub 2020 Aug 28.
OBJECTIVE/BACKGROUND: Stroke is often considered a risk factor for central sleep apnea (CSA). The goal of this study was to determine the prevalence and clinical correlates of CSA in patients with ischemic stroke.
PATIENTS/METHODS: In this analysis, 1346 participants in the Brain Attack Surveillance in Corpus Christi (BASIC) project underwent a home sleep apnea test shortly after ischemic stroke. Respiratory events during sleep were classified as central apneas, obstructive apneas, or hypopneas. Central apnea index (CAI) was defined as number of central apneas divided by recording time. CSA was defined as CAI ≥5/hour with at least 50% of all scored respiratory events classified as central apneas. Demographics and co-morbidities were ascertained from the medical record.
Median CAI was 0/hour. Nineteen participants (1.4%) met criteria for CSA. Participants with CSA were more likely to be male, and had lower prevalence of obesity than participants without CSA. There was no association between CSA and other co-morbidities.
CSA was uncommon in this large cohort of patients with recent ischemic stroke.
目的/背景：中风通常被认为是中枢性睡眠呼吸暂停（CSA）的一个危险因素。本研究的目的是确定缺血性中风患者中 CSA 的患病率和临床相关性。
患者/方法：在这项分析中，脑卒中专案监测项目（BASIC）中的 1346 名参与者在缺血性中风后不久接受了家庭睡眠呼吸暂停测试。睡眠期间的呼吸事件被分类为中枢性呼吸暂停、阻塞性呼吸暂停或低通气。中枢性呼吸暂停指数（CAI）定义为中枢性呼吸暂停次数除以记录时间。CSA 定义为 CAI≥5/小时，且至少 50%的所有评分呼吸事件被分类为中枢性呼吸暂停。从病历中确定人口统计学和合并症。
中位 CAI 为 0/小时。19 名参与者（1.4%）符合 CSA 的标准。与无 CSA 的参与者相比，CSA 患者更可能为男性，且肥胖的患病率更低。CSA 与其他合并症之间没有关联。
在这个最近发生缺血性中风的大型患者队列中，CSA 并不常见。
