Arbeille P, Patat F, Tranquart F, Body G, Berson M, Roncin A, Saliba E, Magnin G, Berger C, Pourcelot L
J Gynecol Obstet Biol Reprod (Paris). 1987;16(1):45-51.
Umbilical circulation can be explored by Doppler ultrasound methods very easily. The umbilical arteries spectrum provides information on the placental circulation. The diastolic flow is directly related to the vascular resistances of the placenta (Rp). In cases of pathological pregnancies with hypertension the decrease in the diastolic flow and the increase in the resistance index Rp have been correlated with intra-uterine fetal growth retardation. The specificity of this index Rp is of 95% but the sensitivity much more lower (approximately 70%). For that reason Doppler assessment of the fetal circulation in other areas has been recently carried out. Fetal cerebral arteries have been explored during normal pregnancies. The index of cerebral resistances as defined by Pourcelot Rc = S-D divided by S (with S systolic amplitude and D diastolic amplitude) show similar variations to the placental index but later in the pregnancy. During the pregnancy the cerebral index is higher than the placental one and the cerebro placental ratio (CPR) superior to 1. During pathological pregnancy (hypertension) with fetal growth retardation one of the index Rc or Rp may be out of the normal range but the cerebro placental ratio CPR is always lower than 1. The follow up of both the umbilical and cerebral circulation increases notably the accuracy of the Doppler method for the detection of intra-uterine fetal growth retardation.
脐循环可通过多普勒超声方法轻松探测。脐动脉频谱可提供胎盘循环的相关信息。舒张期血流与胎盘的血管阻力(Rp)直接相关。在患有高血压的病理妊娠病例中,舒张期血流减少以及阻力指数Rp升高与宫内胎儿生长受限相关。该指数Rp的特异性为95%,但敏感性则低得多(约70%)。因此,最近已对胎儿其他部位的循环进行了多普勒评估。在正常妊娠期间对胎儿脑动脉进行了探测。由普尔塞洛定义的脑阻力指数Rc =(S - D)/S(其中S为收缩期振幅,D为舒张期振幅)显示出与胎盘指数相似的变化,但在妊娠后期出现。在妊娠期间,脑指数高于胎盘指数,脑胎盘比率(CPR)大于1。在伴有胎儿生长受限的病理妊娠(高血压)中,指数Rc或Rp之一可能超出正常范围,但脑胎盘比率CPR始终低于1。对脐循环和脑循环的监测显著提高了多普勒方法检测宫内胎儿生长受限的准确性。