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冥想与音乐聆听对改善乳腺癌幸存者认知功能的随机对照试验:可行性和可接受性。

A randomized control trial of meditation compared to music listening to improve cognitive function for breast cancer survivors: Feasibility and acceptability.

机构信息

The University of Texas at Austin, School of Nursing, 1710 Red River St, Austin, TX, 78712, USA; The University of Texas at Austin, Department of Oncology, 1601 Trinity St, Austin, TX, 78712, USA.

The University of Texas at Austin, School of Nursing, 1710 Red River St, Austin, TX, 78712, USA.

出版信息

Complement Ther Clin Pract. 2020 Nov;41:101228. doi: 10.1016/j.ctcp.2020.101228. Epub 2020 Sep 11.

Abstract

BACKGROUND

and Purpose: Many breast cancer survivors (BCS) experience persistent cognitive and psychological changes associated with their cancer and/or treatment and that have limited treatment options. Therefore, the purpose of this study was to explore the feasibility and effects of a Kirtan Kriya meditation (KK) intervention on cognitive and psychological symptoms compared to an attention control condition, classical music listening (ML), in BCS.

MATERIALS AND METHODS

A randomized control trial design was used. Participants completed eight-week interventions. Cognitive function and psychological symptoms were measured at baseline and post-intervention. Mixed analysis of variance models were examined for all cognitive and psychological outcomes.

RESULTS

27 BCS completed the study. Intervention adherence was 88%. Both groups improved in perceived cognitive impairments, cognition related quality of life, verbal memory, and verbal fluency (p's < 0.01). There were no significant group by time effects for cognitive and psychological outcomes, except stress. The ML group reported lower stress at time 2 (p < 0.05).

CONCLUSION

KK and ML are feasible, acceptable, and cost-effective interventions that may be beneficial for survivors' cognition and psychological symptoms. Both interventions were easy to learn, low cost, and required just 12 min/day. Meditation or music listening could offer providers evidence-based suggestions to BCS experiencing cognitive symptoms.

CLINICAL TRIALS REGISTRATION NUMBER

NCT03696056.

摘要

背景和目的

许多乳腺癌幸存者(BCS)经历与癌症和/或治疗相关的持续认知和心理变化,且治疗选择有限。因此,本研究的目的是探索与注意力控制条件(经典音乐聆听,ML)相比,Kirtan Kriya 冥想(KK)干预对 BCS 的认知和心理症状的可行性和效果。

材料和方法

采用随机对照试验设计。参与者完成了为期八周的干预。在基线和干预后测量认知功能和心理症状。对所有认知和心理结果进行混合方差分析模型检验。

结果

27 名 BCS 完成了研究。干预依从性为 88%。两组在感知认知障碍、认知相关生活质量、言语记忆和言语流畅性方面均有所改善(p 值均<0.01)。除了压力,认知和心理结果均无显著的组间时间效应。ML 组在第 2 时间报告的压力较低(p<0.05)。

结论

KK 和 ML 是可行的、可接受的、具有成本效益的干预措施,可能有益于幸存者的认知和心理症状。两种干预措施都易于学习,成本低,每天只需 12 分钟。对于经历认知症状的 BCS,冥想或音乐聆听可以为提供者提供基于证据的建议。

临床试验注册号

NCT03696056。

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