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老年人暴露于绿地与死亡率和心血管结局的关系:观察性研究的系统评价和荟萃分析。

Green space exposure on mortality and cardiovascular outcomes in older adults: a systematic review and meta-analysis of observational studies.

机构信息

The Shengli Clinical Medical College, Fujian Medical University, Fuzhou, China.

Department of Geriatric Medicine, Fujian Provincial Hospital, Fuzhou, China.

出版信息

Aging Clin Exp Res. 2021 Jul;33(7):1783-1797. doi: 10.1007/s40520-020-01710-0. Epub 2020 Sep 19.

Abstract

BACKGROUND

With the launch of the "Global Age-Friendly Cities project", increasing emphasis has been placed on the effects of green spaces on health in the elderly. The previous literature has shown that green spaces are beneficial to a range of health-related outcomes in adults. However, associations of greenness with mortality and cardiovascular outcomes are less certain, which may differ depending on the age class. This review aimed to synthesize current evidence from observational studies to assess relationships of green space exposure with mortality and cardiovascular outcomes in older individuals.

METHODS

Five databases were searched. Qualitative evaluation and meta-analyses of included studies were conducted. This review is registered with PROSPERO, CRD42020160366.

RESULTS

Of the 8,143 records identified, we finally included 22 studies. In a narrative systematic review, we observed that the majority of studies showed reductions in the risk of all-cause mortality and total cardiovascular disease. Further meta-analyses which included eight cohort studies, indicated that greater greenness exposure (per 0.1 unit increase of normalized difference vegetation index (NDVI)) was associated with a reduced risk of all-cause mortality (pooled hazard ratios (HR) (95% confidence interval (CI) = 0.99 (0.97, 1.00)) and stroke mortality (pooled HR (95% CI) = 0.77 (0.59, 1.00)) in older individuals.

CONCLUSIONS

This review supports increasing green space exposure in terms of the prevention of death and cardiovascular outcomes in older individuals. Effective measures to increase or preserve greenspaces should therefore be considered as important public health interventions.

摘要

背景

随着“全球宜居城市计划”的推出,人们越来越关注绿色空间对老年人健康的影响。之前的文献表明,绿色空间有益于一系列与健康相关的成年人的结果。然而,绿色空间与死亡率和心血管结果的关联尚不确定,这可能因年龄组而异。本综述旨在综合目前的观察性研究证据,评估老年人暴露于绿色空间与死亡率和心血管结果的关系。

方法

搜索了五个数据库。对纳入研究进行定性评估和荟萃分析。本综述在 PROSPERO 注册,CRD42020160366。

结果

在确定的 8143 条记录中,我们最终纳入了 22 项研究。在叙述性系统评价中,我们观察到大多数研究显示全因死亡率和总心血管疾病风险降低。进一步纳入八项队列研究的荟萃分析表明,绿色空间暴露量增加(归一化差异植被指数(NDVI)每增加 0.1 单位)与全因死亡率(汇总危险比(HR)(95%置信区间(CI)=0.99(0.97, 1.00))和中风死亡率(汇总 HR(95%CI)=0.77(0.59, 1.00))降低有关。

结论

本综述支持在老年人中增加绿色空间暴露以预防死亡和心血管结果。因此,应考虑采取有效措施增加或保护绿色空间,作为重要的公共卫生干预措施。

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