免疫功能正常患者的广泛耐药结核性脊柱骨髓炎：病例报告。

Pre-extensively drug-resistant tuberculosis spondylodiscitis in an immunocompetent patient: a case report.

机构信息

Department of Rheumatology B, El Ayachi Hospital, Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

Tuberculosis and Respiratory Disease Diagnostic Center, Bab khmiss, Salé, Morocco.

出版信息

Pan Afr Med J. 2020 Jul 8;36:165. doi: 10.11604/pamj.2020.36.165.21689. eCollection 2020.

DOI:10.11604/pamj.2020.36.165.21689

PMID:32952809

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7467892/

Abstract

Pre-extensively drug resistant tuberculosis (pre-XDR-TB) has been an area of growing concern, and posing a threat to global efforts of TB control. We report a case of PreXDR-TB spondylodiscitis with resistance to a Fluoroquinolone, in an immunocompetent patient under antibacillary treatment for pleural tuberculosis, managed with drug sensitivity-based second-line antituberculous drug regimen. Our case shows the challenges of the diagnostic and management of Drug-resistant TB spondylodiscitis.

摘要

广泛耐药结核病前期（pre-XDR-TB）已成为日益关注的领域，对全球结核病控制工作构成威胁。我们报告了一例免疫功能正常的患者在接受抗结核药物治疗胸腔结核时发生氟喹诺酮类药物耐药的 preXDR-TB 脊椎炎，采用基于药敏试验的二线抗结核药物方案进行治疗。我们的病例显示了耐药结核病脊椎炎的诊断和管理的挑战。