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克罗恩病还是组织胞浆菌病?一例酷似克罗恩病的重症播散性组织胞浆菌病病例及文献综述

Crohn's disease or histoplasmosis? A case of severe disseminated histoplasmosis mimicking Crohn's disease and literature review.

作者信息

Ahmed Ahmed, Homsi Nora, Kapila Rajendra

机构信息

Division of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.

Division of Infectious Disease, Rutgers New Jersey Medical School, Newark, NJ, USA.

出版信息

Med Mycol Case Rep. 2020 Aug 28;30:8-11. doi: 10.1016/j.mmcr.2020.08.003. eCollection 2020 Dec.

DOI:10.1016/j.mmcr.2020.08.003
PMID:32953428
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7484513/
Abstract

Disseminated histoplasmosis (DH) often mimics other diseases, leading to misdiagnosis and delays in treatment. We present a patient who developed DH after treatment with immunosuppressants for an initial diagnosis of inflammatory bowel disease (IBD). Upon diagnosing her with DH, liposomal amphotericin B was started, and she eventually recovered after a prolonged hospitalization. Intrabdominal histoplasmosis has many similarities with IBD. Treatment with immunosuppressants in undiagnosed histoplasmosis can lead to dissemination with potentially catastrophic results.

摘要

播散性组织胞浆菌病(DH)常与其他疾病相似,导致误诊和治疗延误。我们报告一名患者,其在因初步诊断为炎症性肠病(IBD)而接受免疫抑制剂治疗后发生了DH。在诊断出她患有DH后,开始使用脂质体两性霉素B治疗,经过长时间住院,她最终康复。腹腔内组织胞浆菌病与IBD有许多相似之处。在未确诊的组织胞浆菌病中使用免疫抑制剂治疗可导致播散,产生潜在的灾难性后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/c8de0a5d5d73/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/c0743ceb1898/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/bd5ef3063ec3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/c8de0a5d5d73/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/c0743ceb1898/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/bd5ef3063ec3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac4c/7484513/c8de0a5d5d73/gr3.jpg

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