Weihai Municipal Hospital, Weihai, China.
Eur Arch Otorhinolaryngol. 2021 Aug;278(8):2665-2672. doi: 10.1007/s00405-020-06369-x. Epub 2020 Sep 21.
Periostin, an extracelluar matrix protein belonging to the fasciclin family, has been reported to play a key role in the process of Th2-inflammation disease. As eoshinophilic chronic rhinosinusitis has a higher incident rate, studies show that periostin has participated in the process of inflammation and remodeling. This review mainly to summarize researches of periostin in ECRS and to investigate the clinical significance and expression of periostin.
骨膜蛋白，一种属于纤维粘连蛋白家族的细胞外基质蛋白，据报道在 Th2 炎症性疾病的发生过程中起着关键作用。嗜酸性慢性鼻-鼻窦炎的发病率较高，研究表明骨膜蛋白参与了炎症和重塑过程。本综述主要总结了骨膜蛋白在 ECRS 中的研究，并探讨了骨膜蛋白的临床意义和表达。
