Tiryaki Demir Semra, Karapapak Murat, Uslu Hasan Sinan, Bulbul Ali, Guven Dilek, Dirim Ayse Burcu, Ustaoglu Melih, Sendul Selam Yekta, Olgun Ali
Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Halaskargazi Cad. Etfal St. 34371 Sisli, Istanbul, Turkey.
Department of Neonatology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Graefes Arch Clin Exp Ophthalmol. 2019 Jun;257(6):1325-1329. doi: 10.1007/s00417-019-04298-y. Epub 2019 Mar 26.
The aim of this retrospective, nonrandomized, observational clinical study was to evaluate the screening results for retinopathy of prematurity (ROP) of late-preterm infants born at 32-35 weeks gestational age (GA).
Retinopathy screening data of late-preterm infants were evaluated between January 2015 and September 2018. The zones and stages of ROP development were classified according to the International ROP Committee criteria. Patients were categorized into four groups according to GA: 32 < 33 weeks GA, 33 < 34 weeks GA, 34 < 35 weeks GA, and 35 < 36 weeks GA. The rates of development of any stage of ROP or severe ROP (requiring treatment) were recorded.
The study included 543 infants: 139 (25.4%) in 32 < 33 weeks GA, 127 (23.6%) in 33 < 34 weeks GA, 162 (30.2%) in 34 < 35 weeks GA, and 115 (20.8%) in 35 < 36 weeks GA. Different stages of ROP developed in 29 infants (20.9%) in 32 < 33 weeks GA, 19 infants (15%) in 33 < 34 weeks GA, 17 infants (10.5%) in 34 < 35 weeks GA, and 6 infants (5.2%) in 35 < 36 weeks GA. Treatment was required for 14 infants (2.6%) due to severe ROP: 7 (5%) in 32 < 33 weeks GA, 3 (2.4%) in 33 < 34 weeks GA, and 4 (2.5%) in 34 < 35 weeks GA. No treatment was required in 35 < 36 weeks GA.
Late-preterm infants must be screened for ROP, especially those born in developing countries. Although rates of ROP development decrease as GA increases, infants born at 34 weeks of GA or younger, regardless of birth weight, should be examined at least once for ROP.
这项回顾性、非随机、观察性临床研究的目的是评估孕龄（GA）为32 - 35周的晚期早产儿的早产儿视网膜病变（ROP）筛查结果。
对2015年1月至2018年9月期间晚期早产儿的视网膜病变筛查数据进行评估。根据国际ROP委员会标准对ROP发展的区域和阶段进行分类。根据GA将患者分为四组：GA 32＜33周、GA 33＜34周、GA 34＜35周和GA 35＜36周。记录ROP任何阶段或严重ROP（需要治疗）的发展率。
该研究纳入了543名婴儿：GA 32＜33周的有139名（25.4%），GA 33＜34周的有127名（23.6%），GA 34＜35周的有162名（30.2%），GA 35＜36周的有115名（20.8%）。GA 32＜33周的29名婴儿（20.9%）出现了不同阶段的ROP，GA 33＜34周的19名婴儿（15%），GA 34＜35周的17名婴儿（10.5%），GA 35＜36周的6名婴儿（5.2%）。因严重ROP有14名婴儿（2.6%）需要治疗：GA 32＜33周的7名（5%），GA 33＜34周的3名（2.4%），GA 34＜35周的4名（2.5%）。GA 35＜36周的婴儿无需治疗。
晚期早产儿必须进行ROP筛查，尤其是在发展中国家出生的婴儿。尽管ROP的发展率随着GA的增加而降低，但GA为34周或更小的婴儿，无论出生体重如何，都应至少接受一次ROP检查。
