针刺联合或不联合艾灸治疗原发性痛经：一项系统评价与Meta分析方案
Acupuncture with or without moxibustion for primary dysmenorrhea: A protocol for a systematic review and meta-analysis.
作者信息
Zhou Xingchen, Xiong Jun, Chi Zhenhai, Hua Fanghui, Lu Lunbin, Chen Jun, Tang Genhua, Zhu Siyuan, Zhong Zhiying, Guo Han
机构信息
The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine.
Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
出版信息
Medicine (Baltimore). 2020 Sep 18;99(38):e22395. doi: 10.1097/MD.0000000000022395.
BACKGROUND
Primary dysmenorrhea (PD) occurs during menstrual cramps, and there is currently no pathological evidence. This disease severely affects the daily lives of young women. Acupuncture (ACU) and moxibustion are an excellent way to relieve the pain of patients with PD. And it has been widely utilizing. However, the effectiveness and safety of ACU and moxibustion in treating patients with PD are not confirmed by a high-quality meta-analysis. This work aims to evaluate ACU's efficacy and safety with or without moxibustion in the management of PD.
METHODS
We will make a comprehensive retrieval in 9 databases as following: Embase; Cochrane Library; PubMed; Chinese databases SinoMed (previously called the Chinese Biomedical Database); Chinese National Knowledge Infrastructure; Chinese Scientific Journals Database; Wanfang Data. The time is limited from the construction of the library to August 2020. No restrictions about language and status. Our 2 authors will perform the selection of studies, the extraction of data, and the quality assessment with the risk of bias tool independently. We will use NoteExpressV3.2.0 and Excel2010 software to extract data. The content will be saved in electronic form. We will use the bias risk tool provided by the Cochrane Collaboration to evaluate the quality of the literature using RevMan 5.4 software. The primary outcome is the pain degree evaluation, including visual analog scale, numerical rating scale, Cox retrospective symptom scale, or any other scale used to evaluate the level of pain.Furthermore, the response rate involved an overall reduction in symptoms. The adverse effects and quality of life will be assessed as secondary outcomes. The risk ratio for dichotomous data and mean differences with a 95% confidence interval for continuous data will be adopted to express the effect and safety of ACU with or without moxibustion for PD.
RESULTS
The results of our study expect to provide high-quality, evidence-based recommendations on further treatment for clinicians.
TRIAL REGISTRATION NUMBER
INPLASY202080006.
CONCLUSION
This study will provide scientific evidence of PD Systematic review.
背景
原发性痛经（PD）发生于月经期间，目前尚无病理学证据。该疾病严重影响年轻女性的日常生活。针灸是缓解PD患者疼痛的一种有效方法，并且已被广泛应用。然而，针灸治疗PD患者的有效性和安全性尚未得到高质量的荟萃分析证实。本研究旨在评估针灸联合或不联合艾灸治疗PD的疗效和安全性。
方法
我们将对以下9个数据库进行全面检索：Embase；Cochrane图书馆；PubMed；中国数据库中国生物医学文献数据库（SinoMed，原中国生物医学数据库）；中国知网；维普中文科技期刊数据库；万方数据。检索时间范围为各数据库建库至2020年8月。不限语言和文献类型。由两位作者独立进行文献筛选、数据提取，并使用偏倚风险工具进行质量评估。我们将使用NoteExpressV3.2.0和Excel2010软件提取数据，内容将以电子形式保存。我们将使用Cochrane协作网提供的偏倚风险工具，采用RevMan 5.4软件评估文献质量。主要结局是疼痛程度评估，包括视觉模拟量表、数字评定量表、Cox回顾性症状量表或任何其他用于评估疼痛程度的量表。此外，缓解率涉及症状的总体减轻。不良反应和生活质量将作为次要结局进行评估。对于二分类数据采用风险比，对于连续数据采用95%置信区间的均值差来表示针灸联合或不联合艾灸治疗PD的疗效和安全性。
结果
我们的研究结果期望为临床医生提供关于进一步治疗的高质量、循证医学建议。
试验注册号
INPLASY202080006。
结论
本研究将为PD的系统评价提供科学证据。
Zotero 插件