Wu Zenan, Yang Yi, Xiong Jun, Yu Xinyu, Zuo Zhengyun, Xie Qiongshan
Jiangxi University of Traditional Chinese Medicine.
The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Medicine (Baltimore). 2020 Aug 28;99(35):e21713. doi: 10.1097/MD.0000000000021713.
Primary dysmenorrhea (PD), also called functional dysmenorrhea, refers to a woman's menstrual period in genital no organic disease, abdominal pain, under the belly and other discomfort for the characteristics of disease of department of gynecology. Acupuncture and moxibustion have been accepted as treatment options for PD. So far, there are so many therapies for PD and their efficacy has been assessed by several systematic reviews. Therefore, this study aims at evaluating the effectiveness which acupuncture and moxibustion technique is more effective for primary dysmenorrhea.
The following electronic databases will be searched in this study: the Cochrane Central Register of Controlled Trials (CENTRAL);PubMed; EMBASE; China National Knowledge Infrastructure (CNKI); Chinese Biomedical Literature Database (CBM);Chinese Scientific Journal Database (VIP database); and Wan-Fang Database(WF). More than two authors independently assessed the quality of the evidence by AMSTAR2, PRISMA, PRISMA-A, and GRADE approach. Two of our researchers will use the bias risk tool provided by the Cochrane Collaboration to evaluate the quality of the literature using WinBUGS 1.4.3 and STATA softwares. The primary outcomes include the extent of pain in the lower abdomen measured by visual analog scale (VAS) and relief from symptoms. The quality of life (QoL) and Adverse events will be considered as Additional outcome(s). Their reference lists and the citation lists of studies meeting the inclusion criteria and relevant systematic reviews will also be searched to identify further studies for inclusion. Before this review completed, the 2 reviewers will conduct the search once again to ensure the latest studies could be included.
This review does not require ethical approval.
The results will be published in a peer-reviewed journal.
This study will provide comprehensive evidence of acupuncture and moxibustion for patients with PD.
INPLASY2020500106.
原发性痛经（PD），又称功能性痛经，是指女性在经期生殖器官无器质性病变，以腹部疼痛、下腹坠胀等不适为特征的妇科疾病。针灸已被公认为治疗原发性痛经的方法之一。目前，针对原发性痛经的治疗方法众多，且已有多项系统评价对其疗效进行了评估。因此，本研究旨在评估针灸技术对原发性痛经的有效性，比较哪种针灸技术更有效。
本研究将检索以下电子数据库：Cochrane系统评价数据库（CENTRAL）、PubMed、EMBASE、中国知网（CNKI）、中国生物医学文献数据库（CBM）、维普中文科技期刊数据库（VIP数据库）和万方数据库（WF）。由两名以上作者独立采用AMSTAR2、PRISMA、PRISMA - A和GRADE方法评估证据质量。我们的两名研究人员将使用Cochrane协作网提供的偏倚风险工具，通过WinBUGS 1.4.3和STATA软件评估文献质量。主要结局包括采用视觉模拟评分法（VAS）测量的下腹疼痛程度和症状缓解情况。生活质量（QoL）和不良事件将作为附加结局。还将检索纳入研究的参考文献列表以及符合纳入标准的研究和相关系统评价的引用列表，以确定更多可纳入的研究。在本综述完成之前，两名评审员将再次进行检索，以确保纳入最新的研究。
本综述无需伦理批准。
研究结果将发表在同行评审期刊上。
本研究将为原发性痛经患者提供针灸治疗的全面证据。
INPLASY注册号：INPLASY20205001
