针灸治疗周围性面瘫的有效性和安全性：系统评价与Meta分析概述方案
Effectiveness and safety of acupuncture and moxibustion for peripheral facial paralysis: A protocol for an overview of systematic reviews and meta-analysis.
作者信息
Zhou Xingchen, Xiong Jun, Chi Zhenhai, Lu Lunbin, Chen Jun, Tang Genhua, Zhu Siyuan, Zhong Zhiying, Guo Han
机构信息
The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine.
Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
出版信息
Medicine (Baltimore). 2020 Sep 18;99(38):e22371. doi: 10.1097/MD.0000000000022371.
BACKGROUND
Peripheral facial paralysis (PFP) seriously affects patients' quality of life and work and even causes psychological problems such as anxiety and depression for them. Acupuncture (ACU) and moxibustion have been widely used to treat the disease with satisfactory results. Several systematic reviews and meta-analyses have reported the effectiveness of acupuncture for patients with PFP. However, the evidence has not been systematically synthesized. This overview aims to synthesize and assess the reliability of evidence generated from these systematic reviews (SRs) and meta-analyses of ACU and moxibustion for PFP.
METHODS
We will make a comprehensive retrieval in 9 databases as following: (1) Embase; (2) Cochrane Library; (3) Pubmed; (4) Chinese databases SinoMed (previously called the Chinese Biomedical Database); (5) Chinese National Knowledge Infrastructure (CNKI); (6) Chinese Scientific Journals Database (VIP); (7) Wanfang Data (WF). The time is limited from the construction of the library to August 2020. We will use the Assessment of Multiple Systematic Reviews-2 (AMSTAR-2) tool to evaluate methodological quality. Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols (PRISMA-P) will be used in the report checklist to assess the quality of reports in the study. The Grading of the Classification of Recommendations, Evaluation, Development and Evaluation (GRADE) will be used to evaluate the included SRs and meta-analysis. Our reviewers will conduct systematic reviews, qualification evaluation, data extraction, methodological quality and evidence quality screening in pairs. The outcomes of interest include: the effective rate, the House-Brackmann (H-B) score, cure rate, and side effects. Or any other scale used to assess the level of illness. The evidence will be synthesized where appropriate based on patient subgroups and outcomes.
RESULTS
The results will be published in a peer-reviewed journal.
CONCLUSION
This overview will provide comprehensive evidence of ACU and moxibustion for patients with PFP.
TRIAL REGISTRATION NUMBER
INPLASY202080016.
背景
周围性面瘫（PFP）严重影响患者的生活质量和工作，甚至给他们带来焦虑和抑郁等心理问题。针灸已被广泛用于治疗该疾病，效果令人满意。几项系统评价和荟萃分析报告了针灸治疗PFP患者的有效性。然而，相关证据尚未得到系统整合。本综述旨在整合和评估这些关于针灸和艾灸治疗PFP的系统评价（SRs）和荟萃分析所产生证据的可靠性。
方法
我们将在以下9个数据库中进行全面检索：（1）Embase；（2）Cochrane图书馆；（3）Pubmed；（4）中国数据库中国生物医学文献数据库（SinoMed，原中国生物医学数据库）；（5）中国知网（CNKI）；（6）维普中文科技期刊数据库（VIP）；（7）万方数据（WF）。检索时间范围为各数据库建库至2020年8月。我们将使用多重系统评价评估工具2（AMSTAR - 2）来评估方法学质量。系统评价和荟萃分析优先报告条目（PRISMA - P）将用于报告清单，以评估研究报告的质量。推荐分级的评估、制定与评价（GRADE）将用于评估纳入的SRs和荟萃分析。我们的评审人员将成对进行系统评价、资格评估、数据提取、方法学质量和证据质量筛选。感兴趣的结局包括：有效率、House - Brackmann（H - B）评分、治愈率和副作用。或者用于评估病情程度的任何其他量表。将根据患者亚组和结局在适当情况下对证据进行整合。
结果
结果将发表在同行评审期刊上。
结论
本综述将为PFP患者提供关于针灸和艾灸的全面证据。
试验注册号
INPLASY202080016。
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