Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.
Aix Marseille Univ, IRD, AP-HM, SSA, VITROME, Marseille, France.
J Epidemiol Glob Health. 2021 Mar;11(1):69-75. doi: 10.2991/jegh.k.200723.001. Epub 2020 Jul 29.
The objective of this study was to describe the overall pattern of morbidity and mortality of children seen at the Thai Binh Paediatric Hospital in Vietnam, with a focus on infectious diseases. A retrospective review of hospitalisation records was conducted from 1 January 2015 to 31 December 2019. Data were obtained from a total of 113,999 records. The median age of patients was 18 months, with 84.0% of patients aged <5 years. Infectious diseases accounted for 61.0% of all cases. The most prevalent diseases were lower respiratory tract infections (32.8%), followed by gastrointestinal infections (13.3%) and confirmed influenza (5.4%). Most infections were not microbiologically documented. A total of 81.4% patients received at least one antibiotic. Most patients (97.0%) were hospitalised for less than 15 days. Regarding outcomes, 87.8% patients were discharged home with a favourable outcome. Twelve percent were transferred to the Vietnam National Children's Hospital because their condition had worsened and 0.1% died. In total, infectious diseases accounted for 40.4% of deaths, followed by neonatal disorders (34.6%). Our data serves a basis for the identification of needs for diagnostic tools and for future evaluation of the effect of the targeted implementation of such facilities. Point-of-care tests, including real-time polymerase chain reaction assays to identify common pathogens should be implemented for more accurate diagnosis and more appropriate antibiotic use.
本研究旨在描述越南堤岸儿科医院就诊儿童的总体发病和死亡模式,重点关注传染病。对 2015 年 1 月 1 日至 2019 年 12 月 31 日的住院记录进行了回顾性分析。共获得了 113999 例患者的数据。患者的中位年龄为 18 个月,84.0%的患者年龄<5 岁。传染病占所有病例的 61.0%。最常见的疾病是下呼吸道感染(32.8%),其次是胃肠道感染(13.3%)和确诊流感(5.4%)。大多数感染未进行微生物学证实。共有 81.4%的患者至少使用了一种抗生素。大多数患者(97.0%)住院时间不到 15 天。在结局方面,87.8%的患者出院时情况良好。12%的患者因病情恶化转至越南国家儿童医院,0.1%的患者死亡。总的来说,传染病占死亡病例的 40.4%,其次是新生儿疾病(34.6%)。我们的数据为确定诊断工具的需求以及未来评估此类设施的针对性实施效果提供了依据。应实施即时聚合酶链反应检测等床边检测,以更准确地诊断和更合理地使用抗生素。