Nguyen Le Cam Anh, Duong Khanh Linh, Bui Duc Manh, Le Kieu Dung, Dang Khanh Linh, Nguyen Trung Kien, Gautret Philippe, Hoang Van Thuan, Dao Thi Loi
Thai Binh University of Medicine and Pharmacy, Thai Binh, Vietnam.
IHU-Méditerranée Infection, Marseille, France.
IJID Reg. 2024 Aug 14;12:100426. doi: 10.1016/j.ijregi.2024.100426. eCollection 2024 Sep.
To investigate the prevalence and risk factors associated with infection in Vietnamese children.
Children under 16 years old with gastrointestinal symptoms underwent esophagogastroduodenoscopy and infection was diagnosed using rapid urease test.
A total of 246 children with gastrointestinal symptoms were included. The mean age was 8.4 ± 2.6 years. A total 81.3% tested positive for Children infected with had a lower rate of nausea but a higher rate of lesions in the duodenal bulb and nodular lesions than children without infection (26.5% vs 45.6%, <0.01; 40.0% vs 23.9%; = 0.04; and 68.5% vs 30.3%, <0.0001, respectively). Compared with children aged under 5 years, children aged 11 years and older were four times more likely to be infected with , with odds ratio (OR) 3.50, 95% confidence interval (CI) 1.07-11.39, = 0.04. Washing hands with soap was associated with a reduced risk of infection by three times (OR 0.35, 95% CI 0.17-0.69, = 0.002). Children living in a family where members had a history of infection were nine times more likely to be infected with (OR 8.87, 95% CI 1.15-68.45, = 0.04).
The prevalence of infection in Vietnamese children with gastroenteritis is high. Our results identified several risk factors and emphasize the role of handwashing with soap before eating and after using the toilet in reducing the risk of infection in children.
调查越南儿童感染的患病率及相关危险因素。
对16岁以下有胃肠道症状的儿童进行食管胃十二指肠镜检查，并采用快速尿素酶试验诊断感染。
共纳入246例有胃肠道症状的儿童。平均年龄为8.4±2.6岁。总共81.3%的检测呈阳性。感染的儿童恶心发生率较低，但十二指肠球部病变和结节性病变的发生率高于未感染的儿童（分别为26.5%对45.6%，P<0.01；40.0%对23.9%，P = 0.04；68.5%对30.3%，P<0.0001）。与5岁以下儿童相比，11岁及以上儿童感染的可能性高4倍，比值比（OR）为3.50，95%置信区间（CI）为1.07 - 11.39，P = 0.04。用肥皂洗手可使感染风险降低3倍（OR 0.35，95% CI 0.17 - 0.69，P = 0.002）。家庭成员有感染病史的家庭中的儿童感染的可能性高9倍（OR 8.87，95% CI 1.15 - 68.45，P = 0.04）。
越南患肠胃炎儿童的感染患病率较高。我们的结果确定了几个危险因素，并强调了饭前便后用肥皂洗手在降低儿童感染风险方面的作用。
