Determination of phthalate esters in breast milk before and after frozen storage in milk storage bags.

This study describes the migration of 20 phthalates from breast milk storage bags to breast milk after storage frozen for 1 to 6 months. Analysis of the investigated phthalates was performed by GC-MS/MS. Nine phthalates were found in some of the 27 breast milk storage bags, six phthalates were detected in some of the 40 breast milk samples, but the concentrations were low, except for one sample, which contained dibutyl phthalate (DBP) at the level of 211.2 µg/kg. For most of the breast milk samples stored in breast milk storage bags, the migration of diisobutyl phthalate (DIBP), DBP and di-ethyl-hexyl phthalate (DEHP) increased with increasing storage time, but the migration of DBP and DEHP was lower than the migration limits of 300 µg/kg and 1500 µg/kg from the National Standards of the PRC even after storage for six months. The average daily intakes of DMP, DEP, DIBP, DBP and DEHP were 0.099, 0.39, 0.62, 2.89 and 1.13 µg/kg/d, respectively, and the hazard indices were far below 1.