Department of Chemistry, The American University in Cairo, New Cairo 11835, Egypt.
Department of Chemistry, The American University in Cairo, New Cairo 11835, Egypt.
Sci Total Environ. 2018 Mar 15;618:142-150. doi: 10.1016/j.scitotenv.2017.10.337. Epub 2017 Nov 8.
The occurrence and concentrations of six common phthalates were investigated for the first time in bottled water locally produced in the Egyptian market. The compounds investigated were dimethyl phthalate (DMP), diethyl phthalate (DEP), dibutyl phthalate (DBP), n-butyl benzyl phthalate (BBP), diethyl hexyl phthalate (DEHP), and Di-n-octyl phthalate (D-n-OP). A set of 108 bottled water samples from six different commercial brands of water bottled in transparent polyethylene terephthalate (PET) plastic bottles with high density polyethylene (HDPE) plastic caps were investigated. Water samples were analyzed immediately after purchasing (~2weeks after production), after being stored at room temperature (25±5°C), in a refrigerator (4±1°C) and outdoor under sun exposure (daylight temperature of 40±5°C). Samples were stored up to six months depending on the tested condition. Among the target compounds, only DEHP and DBP were detected in the samples analyzed immediately after purchasing with a detection frequency of 50 and 58% and mean concentrations of 0.104 and 0.082μgl respectively. Significant positive correlation was obtained between the storage time, temperature and the concentration of phthalate compounds detected in the bottled water, indicating possible migration from the PET plastic material as the source. The estimated contribution of bottled water consumption to the tolerable daily intake (TDI) levels of the two most abundant phthalates observed here for adults and toddlers did not exceed 0.16 and 0.72% for DBP while these values were 0.04 and 0.16% for DEHP respectively. These estimated daily intake values from PET bottled water consumption were far below their respective TDI values and therefore should constitute no adverse health effects.
首次在埃及市场上本地生产的瓶装水中调查了六种常见邻苯二甲酸酯的出现和浓度。所研究的化合物为邻苯二甲酸二甲酯（DMP）、邻苯二甲酸二乙酯（DEP）、邻苯二甲酸二丁酯（DBP）、邻苯二甲酸丁基苄基酯（BBP）、邻苯二甲酸二（2-乙基）己酯（DEHP）和邻苯二甲酸二正辛酯（D-n-OP）。对六个不同商业品牌的 108 个瓶装水样本进行了调查，这些品牌的瓶装水均装在透明的聚对苯二甲酸乙二醇酯（PET）塑料瓶中，瓶盖为高密度聚乙烯（HDPE）塑料。在购买后立即（生产后约 2 周）、在室温（25±5°C）下、在冰箱（4±1°C）中和在户外阳光直射下（40±5°C）对水样进行了分析。根据测试条件，水样可储存长达六个月。在所分析的立即购买的样品中，仅检测到 DEHP 和 DBP，检测频率分别为 50%和 58%，浓度分别为 0.104μgl 和 0.082μgl。在瓶装水中检测到的邻苯二甲酸酯化合物的储存时间、温度与浓度之间存在显著正相关，表明可能从 PET 塑料材料中迁移而来。从 PET 瓶装水中摄入的邻苯二甲酸酯化合物对成人和幼儿的可耐受日摄入量（TDI）水平的贡献估计值不超过 0.16%和 0.72%（DBP），而 DEHP 分别为 0.04%和 0.16%。从 PET 瓶装水消费中获得的这些估计日摄入量远低于各自的 TDI 值，因此不会对健康造成不良影响。
