Hepcidin is described as the master regulator of iron: could its removal by CRRT lead to iron dysmetabolism in the critically ill?
作者信息
Honore Patrick M, Barreto Gutierrez Leonel, Kugener Luc, Redant Sebastien, Attou Rachid, Gallerani Andrea, De Bels David
机构信息
ICU Department, Centre Hospitalier Universitaire Brugmann, Brugmann University Hospital, Place Van Gehuchtenplein, 4, 1020, Brussels, Belgium.
出版信息
Crit Care. 2020 Sep 22;24(1):570. doi: 10.1186/s13054-020-03295-6.
Abstract
摘要
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Hepcidin is described as the master regulator of iron: could its removal by CRRT lead to iron dysmetabolism in the critically ill?铁调素被描述为铁的主要调节因子：连续性肾脏替代治疗（CRRT）清除铁调素会导致危重症患者铁代谢紊乱吗？
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本文引用的文献
1
Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing.揭开血浆中铁调素蛋白结合之谜：来自腹膜平衡试验的证据。
Pharmaceuticals (Basel). 2019 Aug 23;12(3):123. doi: 10.3390/ph12030123.
2
Iron Metabolism: An Emerging Therapeutic Target in Critical Illness.铁代谢：危重症治疗的新靶点
Crit Care. 2019 Mar 9;23(1):81. doi: 10.1186/s13054-019-2373-1.
3
Iron, Hepcidin, and Death in Human AKI.铁、hepcidin 和人类急性肾损伤的死亡。
J Am Soc Nephrol. 2019 Mar;30(3):493-504. doi: 10.1681/ASN.2018100979. Epub 2019 Feb 8.
4
A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from The Intensive Care Over Nations audit.一项全球性多中心研究评估了 ICU 入院时合并或不合并脓毒症的危重症患者急性肾损伤恶化或改善对临床结局的影响：来自多国重症监护评估研究的结果。
Crit Care. 2018 Aug 3;22(1):188. doi: 10.1186/s13054-018-2112-z.
5
The removal of serum hepcidin by different dialysis membranes.不同透析膜对血清铁调素的清除作用。
Int J Artif Organs. 2013 Oct 3;36(9):633-9. doi: 10.5301/ijao.5000221. Epub 2013 Aug 2.
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