Lee Seul, Lee Yongjae, Han Sang Yun, Bae Nayoung, Hwang Minwoo, Lee Jeongyun, Chae Han
School of Korean Medicine, Pusan National University, Yangsan 50612, Republic of Korea.
Department of Sasang Constitutional Medicine, Pusan National University Korean Medicine Hospital, Yangsan 50612, Republic of Korea.
Evid Based Complement Alternat Med. 2020 Sep 9;2020:7313581. doi: 10.1155/2020/7313581. eCollection 2020.
The Sasang type-specific pathophysiological symptom is pivotal for the Sasang type classification and pattern identification. The Sasang Urination and Defecation Inventory (SUDI) for urinary function analysis was developed; however, the clinical usefulness of urination-related subscales of SUDI in the Sasang type and Cold-Heat subgroup was not reported with acceptable validation analysis.
The clinical diagnosis of the Sasang type and Cold-Heat subgroup, responses to SUDI items, and weight and height of the 350 hospital patients were acquired retrospectively. The Sasang Urination Inventory (SUI) with SUI-CHR (problematic physical characteristics of urine), SUI-HSS (hypersensitivity of urinary urgency and high frequency), and SUI-DIS (urinary discomfort of hesitancy and residual urine sense) subscales using 12 items of SUDI were improvised. The item and construct validity of the SUI were examined using item response theory and confirmatory factor analysis, and the clinical usefulness of the SUI in Sasang type and Cold-Heat subgroup differentiation was attested.
The SUI and its subscales showed acceptable structural validity and have clinical usefulness in the Tae-Eum type. The Tae-Eum type has a significantly higher SUI-CHR score than did the So-Yang type, and the Heat subgroup has a significantly higher SUI-HSS score than did the Cold subgroup in the Tae-Eum type. . The distinctive Sasang type- and Cold-Heat subscale-specific pathological symptoms in urinary function were revealed using the SUI. The SUI combined with objective Sasang typology measures might be useful for integrative precision medicine combining Eastern and Western practice and for evidence-based clinical education for medical professions.
体质类型特异性病理生理症状对于体质类型分类和证型辨别至关重要。已开发出用于尿液功能分析的体质排尿与排便量表(SUDI);然而,SUDI中与排尿相关分量表在体质类型和寒热亚组中的临床效用尚未通过可接受的效度分析进行报道。
回顾性收集350例住院患者的体质类型和寒热亚组的临床诊断、对SUDI项目的回答以及体重和身高数据。利用SUDI的12个项目,临时编制了包含SUI-CHR(尿液的问题性身体特征)、SUI-HSS(尿急和尿频过敏)和SUI-DIS(排尿犹豫和残余尿感的排尿不适)分量表的体质排尿量表(SUI)。采用项目反应理论和验证性因素分析检验SUI的项目效度和结构效度,并验证SUI在体质类型和寒热亚组鉴别中的临床效用。
SUI及其分量表显示出可接受的结构效度,在太阴人类型中具有临床效用。太阴人类型的SUI-CHR得分显著高于少阳人类型,在太阴人类型中,热亚组的SUI-HSS得分显著高于寒亚组。利用SUI揭示了排尿功能中独特的体质类型和寒热亚组特异性病理症状。SUI结合客观的体质类型测量方法可能有助于东西方结合的综合精准医学以及医学专业的循证临床教育。