Rheumatology Department, Mohammed VI University Hospital, Faculty de Medicine, Mohammed I University, Oriental, Oujda, Morocco.
Pain Res Manag. 2020 Sep 7;2020:5763080. doi: 10.1155/2020/5763080. eCollection 2020.
Many of our rheumatic patients report that weather and seasons affect their symptoms.
The purpose of this study was to examine the effect of meteorological parameters within seasons on rheumatoid arthritis (RA) symptoms.
A retrospective longitudinal study from July 2017 to August 2018 was conducted. Data from three consultations for three seasons were collected and included a tender and swollen joint count, a disease activity score for 28 joints (DAS28), and patient's pain assessment from their computerized medical record. The weather conditions (minimum and maximum temperature, precipitation, humidity, atmospheric pressure, and wind speed) registered during the same day of consultation for each patient were obtained. Then, the statistical correlation between each meteorological parameter and RA parameters was determined using the multiple linear regression analysis.
The data of 117 patients with a mean age of 50.45 ± 12.17 years were analyzed. The mean DAS28 at baseline was 2.44 ± 0.95. The winter in Oujda is cold (average temperature between 10°C and15°C) compared to summer (24.5°C-32.7°C). The spring is wetter with a 71% average humidity. Overall, the tender joint count was significantly correlated with hygrometry (=0.027) in winter. A similar result was obtained in summer with precipitation (=0.003). The pain intensity in the summer was negatively correlated with minimum temperatures and atmospheric pressure. However, there was no correlation between meteorological parameters and disease objective parameters for all seasons. Multiple linear regression analysis showed that weather parameters appeared to explain the variability in four RA predictors in the summer. No significant associations were observed in the spring.
Our study supported the physicians' assumption regarding the effect of climate on pain in RA patients.
我们的许多风湿患者报告说天气和季节会影响他们的症状。
本研究旨在探讨季节内气象参数对类风湿关节炎（RA）症状的影响。
进行了一项回顾性纵向研究，时间为 2017 年 7 月至 2018 年 8 月。收集了三个季节的三次就诊的数据，包括压痛关节和肿胀关节计数、28 个关节疾病活动评分（DAS28）以及患者从计算机病历中对疼痛的评估。为每位患者获得了就诊当天记录的天气条件（最低和最高温度、降水、湿度、大气压和风速）。然后，使用多元线性回归分析确定每个气象参数与 RA 参数之间的统计相关性。
共分析了 117 例平均年龄为 50.45±12.17 岁的患者的数据。基线时 DAS28 的平均值为 2.44±0.95。与夏季（24.5°C-32.7°C）相比，欧杰达的冬季寒冷（平均温度在 10°C 和 15°C 之间）。春季湿度较高，平均湿度为 71%。总体而言，冬季压痛关节计数与湿度呈显著相关（=0.027）。夏季与降水也得到了类似的结果（=0.003）。夏季疼痛强度与最低温度和大气压呈负相关。然而，在所有季节，气象参数与疾病客观参数之间均无相关性。多元线性回归分析显示，夏季天气参数似乎可以解释 RA 预测因子的四个变异性。在春季没有观察到显著的相关性。
本研究支持医生关于气候对 RA 患者疼痛影响的假设。
