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一名患有脑室腹腔分流术的脑积水患者发生广泛耐药（XDR）阑尾周围相关感染：病例报告

Extensive drug resistant (XDR) parappendicular-related infection in a hydrocephalus patient with ventriculoperitoneal shunt: a case report.

作者信息

Cucunawangsih Cucunawangsih, Vatvani Akhil Deepak, Waren Kalis

机构信息

Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia.

Department of Microbiology, Faculty of Medicine, Universitas Pelita Harapan, Tangerang, Indonesia.

出版信息

Pan Afr Med J. 2020 Jul 27;36:218. doi: 10.11604/pamj.2020.36.218.24822. eCollection 2020.

DOI:10.11604/pamj.2020.36.218.24822
PMID:32963684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7490132/
Abstract

Ventricular infection due to XDR-Acinetobacter baumanii (A. baumanii) is the most severe complication after neurosurgery which associated with high morbidity and mortality. Managing A. baumanii ventriculitis/shunt infection and multiple brain abscesses is challenging since its nature that tends to be pandrug resistant to all antibiotics used. Thus, we present the first such case with problems in administration based on the available data.

摘要

耐多药鲍曼不动杆菌引起的脑室感染是神经外科手术后最严重的并发症，与高发病率和死亡率相关。治疗鲍曼不动杆菌性脑室炎/分流感染和多发性脑脓肿具有挑战性，因为其本质上往往对所有使用的抗生素都具有泛耐药性。因此，我们根据现有数据首次报道了这样一例在治疗方面存在问题的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b1/7490132/2656bd889a0f/PAMJ-36-218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b1/7490132/2656bd889a0f/PAMJ-36-218-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8b1/7490132/2656bd889a0f/PAMJ-36-218-g001.jpg

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本文引用的文献

1
Treatment of severe ventriculitis caused by extensively drug-resistant by intraventricular lavage and administration of colistin.通过脑室内灌洗和使用黏菌素治疗广泛耐药菌引起的严重脑室炎。
Infect Drug Resist. 2019 Jan 21;12:241-247. doi: 10.2147/IDR.S186646. eCollection 2019.
2
Case Report of Successful Treatment of Extensively Drug-Resistant Acinetobacter baumannii Ventriculitis with Intravenous plus Intraventricular Tigecycline.静脉联合脑室内注射替加环素成功治疗广泛耐药鲍曼不动杆菌性脑室炎的病例报告
Antimicrob Agents Chemother. 2018 Oct 24;62(11). doi: 10.1128/AAC.01625-18. Print 2018 Nov.
3
Multidrug Resistant Brain Abscess Due to Ventriculitis Cleared by Intraventricular and Intravenous Tigecycline Therapy: A Case Report and Review of Literature.
因脑室炎导致的多重耐药性脑脓肿经脑室内及静脉注射替加环素治疗后清除：一例报告及文献综述
Front Neurol. 2018 Jun 29;9:518. doi: 10.3389/fneur.2018.00518. eCollection 2018.
4
Treatment of ventriculoperitoneal shunt infection and ventriculitis caused by Acinetobacter baumannii: a case report.鲍曼不动杆菌引起的脑室腹腔分流感染和脑室炎的治疗：一例报告
J Med Case Rep. 2018 May 23;12(1):141. doi: 10.1186/s13256-018-1680-5.
5
Successful treatment of multicompartmental cerebral ventriculitis caused by .由……引起的多室性脑室炎的成功治疗 。 （原文不完整，翻译至此）
IDCases. 2017 Nov 21;11:1-2. doi: 10.1016/j.idcr.2017.11.005. eCollection 2018.
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2017 Infectious Diseases Society of America's Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis.2017年美国传染病学会医疗相关脑室炎和脑膜炎临床实践指南。
Clin Infect Dis. 2017 Mar 15;64(6):e34-e65. doi: 10.1093/cid/ciw861.
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Colistin and tigecycline for management of external ventricular device-related ventriculitis due to multidrug-resistant Acinetobacter baumannii.多粘菌素和替加环素用于治疗由多重耐药鲍曼不动杆菌引起的与体外心室装置相关的脑室炎。
J Neurosci Rural Pract. 2016 Jul-Sep;7(3):450-2. doi: 10.4103/0976-3147.176194.
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Treatment options for carbapenem-resistant and extensively drug-resistant Acinetobacter baumannii infections.碳青霉烯类耐药和广泛耐药鲍曼不动杆菌感染的治疗选择。
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