多粘菌素和替加环素用于治疗由多重耐药鲍曼不动杆菌引起的与体外心室装置相关的脑室炎。
Colistin and tigecycline for management of external ventricular device-related ventriculitis due to multidrug-resistant Acinetobacter baumannii.
作者信息
Shrestha Gentle Sunder, Tamang Sushil, Paneru Hem Raj, Shrestha Pramesh Sunder, Keyal Niraj, Acharya Subhash Prasad, Marhatta Moda Nath, Shilpakar Sushil
机构信息
Department of Anaesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Department of Surgery, Neurosurgery Unit, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
出版信息
J Neurosci Rural Pract. 2016 Jul-Sep;7(3):450-2. doi: 10.4103/0976-3147.176194.
Abstract
Acinetobacter baumannii is an important cause of nosocomial ventriculitis associated with external ventricular device (EVD). It is frequently multidrug resistant (MDR), carries a poor outcome, and is difficult to treat. We report a case of MDR Acinetobacter ventriculitis treated with intravenous and intraventricular colistin together with intravenous tigecycline. The patient developed nephrotoxicity and poor neurological outcome despite microbiological cure. Careful implementation of bundle of measures to minimize EVD-associated ventriculitis is valuable.
摘要
鲍曼不动杆菌是与外部脑室引流装置（EVD）相关的医院内脑室炎的重要病因。它常常具有多重耐药性（MDR），预后不良，且难以治疗。我们报告一例多重耐药鲍曼不动杆菌脑室炎患者，采用静脉和脑室内注射黏菌素联合静脉注射替加环素进行治疗。尽管微生物学上已治愈，但该患者仍出现了肾毒性且神经功能预后不佳。谨慎实施一系列措施以尽量减少与EVD相关的脑室炎是很有价值的。
相似文献
1
Colistin and tigecycline for management of external ventricular device-related ventriculitis due to multidrug-resistant Acinetobacter baumannii.多粘菌素和替加环素用于治疗由多重耐药鲍曼不动杆菌引起的与体外心室装置相关的脑室炎。
J Neurosci Rural Pract. 2016 Jul-Sep;7(3):450-2. doi: 10.4103/0976-3147.176194.
2
Combination Treatment with Intravenous Tigecycline and Intraventricular and Intravenous Colistin in Postoperative Ventriculitis Caused by Multidrug-resistant Acinetobacter baumannii.静脉注射替加环素联合脑室内及静脉注射多黏菌素治疗多重耐药鲍曼不动杆菌所致术后脑室炎
Cureus. 2019 Jan 15;11(1):e3888. doi: 10.7759/cureus.3888.
3
Multidrug Resistant Brain Abscess Due to Ventriculitis Cleared by Intraventricular and Intravenous Tigecycline Therapy: A Case Report and Review of Literature.因脑室炎导致的多重耐药性脑脓肿经脑室内及静脉注射替加环素治疗后清除：一例报告及文献综述
Front Neurol. 2018 Jun 29;9:518. doi: 10.3389/fneur.2018.00518. eCollection 2018.
4
Intraventricular Tigecycline as a Last Resort Therapy in a Patient with Difficult-to-Treat Healthcare-Associated Ventriculitis: a Case Report.脑室内使用替加环素作为治疗难治性医疗相关脑室炎患者的最后手段：一例报告
SN Compr Clin Med. 2020;2(9):1683-1687. doi: 10.1007/s42399-020-00433-7. Epub 2020 Aug 9.
5
Intraventricular colistin sulphate as a last resort therapy in a patient with multidrug-resistant Acinetobacter baumannii induced post-neurosurgical ventriculitis.脑室注射硫酸黏菌素作为治疗神经外科术后多重耐药鲍曼不动杆菌引起的脑室炎的最后手段。
Br J Clin Pharmacol. 2022 Jul;88(7):3490-3494. doi: 10.1111/bcp.15238. Epub 2022 Feb 7.
6
Successful treatment of extensively drug-resistant ventriculitis with polymyxin B and tigecycline- a case report.多黏菌素 B 和替加环素成功治疗广泛耐药性脑室炎：一例报告。
Antimicrob Resist Infect Control. 2018 Feb 14;7:22. doi: 10.1186/s13756-018-0313-5. eCollection 2018.
7
Successful treatment of pan-drug resistant nosocomial meningitis/ventriculitis by combined intravenous and intrathecal colistin-tigecycline administration: a case series.静脉联合鞘内注射黏菌素-替加环素成功治疗泛耐药医院获得性脑膜炎/脑室炎：病例系列
Infez Med. 2023 Mar 1;31(1):103-107. doi: 10.53854/liim-3101-14. eCollection 2022.
8
First Case Report of Intraventricular Tigecycline in a Neonate With Extensively Drug-resistant Acinetobacter baumannii Ventriculitis.首例新生儿脑室注射替加环素治疗广泛耐药鲍曼不动杆菌脑室炎
Pediatr Infect Dis J. 2019 Aug;38(8):e172-e174. doi: 10.1097/INF.0000000000002348.
9
Intraventricular CNS treatment with Colistin-Tigecycline combination: A case series.脑室中枢神经系统中使用多黏菌素 E-替加环素联合治疗：病例系列。
J Crit Care. 2018 Oct;47:338-341. doi: 10.1016/j.jcrc.2018.07.025. Epub 2018 Jul 30.
10
Successful treatment of multidrug-resistant Acinetobacter baumannii ventriculitis with intrathecal and intravenous colistin.鞘内和静脉注射黏菌素成功治疗多重耐药鲍曼不动杆菌脑室炎。
Minerva Anestesiol. 2010 Nov;76(11):957-60. Epub 2010 May 6.
引用本文的文献
1
Extensive drug resistant (XDR) parappendicular-related infection in a hydrocephalus patient with ventriculoperitoneal shunt: a case report.一名患有脑室腹腔分流术的脑积水患者发生广泛耐药（XDR）阑尾周围相关感染：病例报告
Pan Afr Med J. 2020 Jul 27;36:218. doi: 10.11604/pamj.2020.36.218.24822. eCollection 2020.
2
International Consensus Guidelines for the Optimal Use of the Polymyxins: Endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP).多黏菌素优化使用国际共识指南：获得美国临床药师协会（ACCP）、欧洲临床微生物学和传染病学会（ESCMID）、美国感染病学会（IDSA）、国际抗感染药理学会（ISAP）、重症医学学会（SCCM）和感染病药师学会（SIDP）认可。
Pharmacotherapy. 2019 Jan;39(1):10-39. doi: 10.1002/phar.2209.
3
Multidrug Resistant Brain Abscess Due to Ventriculitis Cleared by Intraventricular and Intravenous Tigecycline Therapy: A Case Report and Review of Literature.因脑室炎导致的多重耐药性脑脓肿经脑室内及静脉注射替加环素治疗后清除：一例报告及文献综述
Front Neurol. 2018 Jun 29;9:518. doi: 10.3389/fneur.2018.00518. eCollection 2018.
4
Therapeutic drug monitoring for colistin therapy in severe multi-resistant intracerebral abscess: A single case study with high-dose colistin and review of literature.重症多重耐药性脑脓肿中多粘菌素治疗的治疗药物监测：一例高剂量多粘菌素单病例研究及文献综述
SAGE Open Med Case Rep. 2017 Jun 19;5:2050313X17711630. doi: 10.1177/2050313X17711630. eCollection 2017.
本文引用的文献
1
Intrathecal/intraventricular colistin in external ventricular device-related infections by multi-drug resistant Gram negative bacteria: case reports and review.鞘内/脑室内注射多粘菌素治疗耐多药革兰阴性菌所致的脑室外引流装置相关感染：病例报告及文献复习
Infection. 2014 Oct;42(5):801-9. doi: 10.1007/s15010-014-0618-0. Epub 2014 Apr 12.
2
Bundle of measures for external cerebral ventricular drainage-associated ventriculitis.外部脑室引流相关性脑室炎的综合防治措施。
Crit Care Med. 2014 Jan;42(1):66-73. doi: 10.1097/CCM.0b013e31829a70a5.
3
Renal and neurological side effects of colistin in critically ill patients.危重症患者中黏菌素的肾和神经毒性作用。
Ann Intensive Care. 2011 May 25;1(1):14. doi: 10.1186/2110-5820-1-14.
4
Post-neurosurgical multidrug-resistant Acinetobacter baumannii meningitis successfully treated with intrathecal colistin. A new case and a systematic review of the literature.神经外科术后多重耐药鲍曼不动杆菌脑膜炎经鞘内注射黏菌素治疗成功。1 例新病例及文献系统回顾。
Int J Infect Dis. 2010 Jul;14(7):e572-9. doi: 10.1016/j.ijid.2009.06.032. Epub 2009 Nov 4.
5
Management of meningitis due to antibiotic-resistant Acinetobacter species.耐抗生素不动杆菌属所致脑膜炎的管理
Lancet Infect Dis. 2009 Apr;9(4):245-55. doi: 10.1016/S1473-3099(09)70055-6.
6
A review of clinical and microbiological outcomes following treatment of infections involving multidrug-resistant Acinetobacter baumannii with tigecycline.用替加环素治疗多重耐药鲍曼不动杆菌感染后的临床和微生物学结果综述。
J Antimicrob Chemother. 2009 Apr;63(4):775-80. doi: 10.1093/jac/dkn555. Epub 2009 Jan 21.
7
Guidelines for the management of severe traumatic brain injury. VII. Intracranial pressure monitoring technology.重型颅脑损伤管理指南。VII. 颅内压监测技术。
J Neurotrauma. 2007;24 Suppl 1:S45-54. doi: 10.1089/neu.2007.9989.
8
Successful treatment of multidrug-resistant Acinetobacter baumannii central nervous system infections with colistin.用黏菌素成功治疗多重耐药鲍曼不动杆菌中枢神经系统感染
J Clin Microbiol. 2005 Sep;43(9):4916-7. doi: 10.1128/JCM.43.9.4916-4917.2005.
9
Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections.黏菌素：多黏菌素用于治疗多重耐药革兰氏阴性菌感染的复兴
Clin Infect Dis. 2005 May 1;40(9):1333-41. doi: 10.1086/429323. Epub 2005 Mar 22.
10
Practice guidelines for the management of bacterial meningitis.细菌性脑膜炎管理实践指南。
Clin Infect Dis. 2004 Nov 1;39(9):1267-84. doi: 10.1086/425368. Epub 2004 Oct 6.
Zotero 插件