From the Neonatology Unit, Department of Pediatrics.
Department of Microbiology.
Pediatr Infect Dis J. 2019 Aug;38(8):e172-e174. doi: 10.1097/INF.0000000000002348.
Multidrug-resistant and extensively drug-resistant Acinetobacter baumannii infections have been increasing as a cause of healthcare-associated infections in the neonatal age group. In this report, we describe a 27-week, 1028 g, preterm neonate with extensively drug-resistant A. baumannii infection complicated by ventriculitis who did not respond to intravenous and intraventricular colistin but did respond after intraventricular tigecycline. This is the first case report describing the use of intraventricular tigecycline in a neonate with ventriculitis.
多重耐药和广泛耐药鲍曼不动杆菌感染已成为新生儿期医源性感染的一个原因。在本报告中，我们描述了一例 27 周、1028 克的早产儿，患有广泛耐药鲍曼不动杆菌感染合并脑室炎，对静脉和脑室内黏菌素治疗无效，但脑室内替加环素治疗有效。这是首例描述脑室炎新生儿使用脑室内替加环素的病例报告。
