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颅功能性运动障碍:病例系列与文献复习。

Cranial Functional Movement Disorders: A Case Series with Literature Review.

机构信息

Department of Neurology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, JLN Marg, New Delhi, IN.

出版信息

Tremor Other Hyperkinet Mov (N Y). 2020 Aug 25;10:33. doi: 10.5334/tohm.352.

Abstract

BACKGROUND

Cranial functional movement disorders (CFMDs) affect the face, eyes, jaw, tongue, and palate.

OBJECTIVES

We aimed to examine our large series of functional movement disorders (FMDs) patients where the cranial muscles were involved to determine their phenomenology and other clinical features.

METHODS

This is a chart review of 26 patients who presented with CFMDs.

RESULTS

There were 16 (61.53%) females and 10 (38.46%) male patients. The mean ± [standard deviation (SD)] age at the presentation was 33.96 ± 16.94 (Range: 11-83) years. The duration of symptoms ranged from one day to 6 years (Mean ±SD: 402.03 ±534.97 days). According to the Fahn-Williams criteria, CFMDs were documented in 24 patients and clinically established in two patients. The facial [38.46% (10/26)] involvement was the most common in our CFMDs patients. Oromandibular [19.23% (5/26)], ocular [15.38% (4/26)], lingual [15.38% (4/26)], speech [15.38% (4/26)] and palatal [(3.85; 1/26)] involvement was also seen. 10 (38.46%) patients also had associated FMD in the extracranial regions. Precipitating factors were present in 84.61% (22/26) of the patients and associated illnesses were present in 42.30% (11/26) of the patients. At 3 months follow-up, 9 (34.61%) patients had improved, 13 (50%) had partial improvement and 4 (15.38%) had no improvement.

CONCLUSIONS

There was a slight female preponderance in our patients. CFMDs are more likely to involve facial muscles. Associated medical conditions like neuropsychiatric disturbances and headaches are frequently present in CFMDs patients. Early clinical diagnosis will avoid unnecessary investigations and allow the patient to seek the right treatment.

摘要

背景

颅功能性运动障碍(CFMDs)影响面部、眼睛、颌部、舌头和上颚。

目的

我们旨在研究大量涉及颅部肌肉的功能性运动障碍(FMD)患者,以确定其表现和其他临床特征。

方法

这是一项对 26 名出现 CFMD 的患者进行的图表回顾。

结果

患者中女性 16 例(61.53%),男性 10 例(38.46%)。就诊时的平均年龄±标准差为 33.96±16.94 岁(范围:11-83 岁)。症状持续时间从一天到 6 年不等(平均±标准差:402.03±534.97 天)。根据 Fahn-Williams 标准,24 例患者被记录为 CFMD,2 例患者被临床确定为 CFMD。在我们的 CFMD 患者中,面部受累最为常见(38.46%,10/26)。口颌部受累(19.23%,5/26)、眼部受累(15.38%,4/26)、舌部受累(15.38%,4/26)、言语受累(15.38%,4/26)和腭部受累(3.85%,1/26)也很常见。10 例(38.46%)患者还存在颅外区域的相关 FMD。84.61%(22/26)的患者存在诱发因素,42.30%(11/26)的患者存在相关疾病。在 3 个月的随访中,9 例(34.61%)患者病情改善,13 例(50%)患者部分改善,4 例(15.38%)患者无改善。

结论

我们的患者中女性略占优势。CFMD 更可能累及面部肌肉。伴有神经精神障碍和头痛等相关疾病的患者经常出现 CFMD。早期临床诊断可以避免不必要的检查,并使患者能够寻求正确的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8553/7485402/1b3da4277794/tohm-10-1-352-g1.jpg

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