对比增强超声与多普勒超声在肾动脉狭窄分级中的价值。
The Value of Contrast-Enhanced Ultrasound versus Doppler Ultrasound in Grading Renal Artery Stenosis.
机构信息
Department of ultrasonic medicine, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Department of ultrasound, Shanxi Provincial People's Hospital, Taiyuan 030012, China.
出版信息
Biomed Res Int. 2020 Sep 8;2020:7145728. doi: 10.1155/2020/7145728. eCollection 2020.
OBJECTIVE
This study is aimed at exploring the accuracy of contrast-enhanced ultrasound (CEUS) in grading renal artery stenosis.
METHODS
122 renal arteries with suspected renal artery stenosis were selected. DSA, DUS, and CEUS were performed for all patients with suspected renal artery stenosis in the research. DSA was selected as the gold standard. The sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) of CEUS or Doppler ultrasound (DUS) in the diagnosis of renal artery stenosis were analyzed. The consistency between CEUS and digital subtraction angiography (DSA) was compared. The accuracy of DUS or CEUS in grading renal artery stenosis was assessed by the area under the receiver operating characteristic (ROC) curves and compared between groups.
RESULTS
The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CEUS in the diagnosis of renal artery stenosis were 88.9%, 87.8%, 88.5%, 93.5%, and 80.0%, respectively. There was no significant difference in grading renal artery stenosis between CEUS and DSA ( = 0.643, = 0.424). 77 of the 122 renal arteries were diagnosed with the stenosis rate more than 30% by CEUS. Compared with the results of DSA, the kappa value of CEUS was 0.749 ( < 0.05).
CONCLUSION
CEUS is accurate in grading renal artery stenosis, and it may represent the method of choice in diagnosing renal artery stenosis.
目的
本研究旨在探讨超声造影（CEUS）在评估肾动脉狭窄程度中的准确性。
方法
选择 122 例疑似肾动脉狭窄的患者。对所有疑似肾动脉狭窄患者进行 DSA、DUS 和 CEUS 检查。以 DSA 为金标准，分析 CEUS 或多普勒超声（DUS）诊断肾动脉狭窄的敏感性、特异性、准确性、阳性预测值（PPV）和阴性预测值（NPV），比较 CEUS 与数字减影血管造影（DSA）的一致性，通过受试者工作特征（ROC）曲线下面积评估 DUS 或 CEUS 分级肾动脉狭窄的准确性，并对各组之间进行比较。
结果
CEUS 诊断肾动脉狭窄的敏感性、特异性、准确性、阳性预测值和阴性预测值分别为 88.9%、87.8%、88.5%、93.5%和 80.0%。CEUS 与 DSA 分级肾动脉狭窄差异无统计学意义（ = 0.643， = 0.424）。CEUS 诊断 122 例患者中有 77 例狭窄率>30%。与 DSA 结果比较，CEUS 的kappa 值为 0.749（ < 0.05）。
结论
CEUS 对肾动脉狭窄分级准确，可能是诊断肾动脉狭窄的首选方法。
Zotero 插件