非诺特罗与沙丁胺醇在哮喘患者中的比较。
Comparison between fenoterol and salbutamol in asthmatic patients.
作者信息
Palma-Carlos A G, Barbosa M A
出版信息
Allergol Immunopathol (Madr). 1977 May-Jun;5(3):227-30.
A comparative study was carried out on 76 asthmatic outpatients concerning their immediate response to the inhalation of Salbutamol and Fenoterol. Bronchodilation was evaluated by repeated peak-flow rate (PFR) determinations. All the patients inhaled two puffs of each of both drugs dispensed by metered aerosols. 131 assays were made and in 18 patients both bronchdilators were used. The mean increase of PFR after Salbutamol (200 microgram) was 15.2% and after Fenoterol (400 microgram), 19.5% this difference not being significant. In 18 patients where both drugs were used the increase in PFR was 19.9% after Fenoterol and 16.7% after Salbutamol. No differences between Fenoterol and Salbutamol in subjective clinical improvement and on pulse rate were observed after the use of these bronchodilators.
对76名哮喘门诊患者吸入沙丁胺醇和非诺特罗的即时反应进行了一项比较研究。通过重复测定峰值流速（PFR）来评估支气管扩张情况。所有患者均吸入定量气雾剂喷出的两种药物各两喷。共进行了131次测定，其中18名患者使用了两种支气管扩张剂。吸入沙丁胺醇（200微克）后PFR的平均增幅为15.2%，吸入非诺特罗（400微克）后为19.5%，差异无统计学意义。在18名使用了两种药物的患者中，吸入非诺特罗后PFR的增幅为19.9%，吸入沙丁胺醇后为16.7%。使用这些支气管扩张剂后，在主观临床改善和脉搏率方面，未观察到非诺特罗和沙丁胺醇之间存在差异。
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