Lundell B P, Kennedy K A, Lindstrom D P, Sundell H, Stahlman M T
Acta Paediatr Scand Suppl. 1986;329:127-33. doi: 10.1111/j.1651-2227.1986.tb10399.x.
The effects of changes in carotid blood flow on intracranial blood flow velocities were examined in six newborn lambs under general anesthesia. Carotid blood flow was measured using electromagnetic flow cuffs. A combined continuous and pulsed Doppler instrument was used to measure intracranial blood flow velocities on the base of the skull through artificially created fontanels. Baseline carotid blood flow was 96 +/- 18 ml X min-1 (mean +/- SD) and increased by 58 +/- 13% following contralateral occlusion. A close correlation between changes in carotid blood flow and intracranial blood flow velocity was found (y = -6.28 + 3.72x, Sy = 182.3, Sy/x = 0.30, r = 0.89, p less than 0.001). The closest estimate of changes in blood flow to the brain was the temporal mean of the cross-sectional average velocity.
在全身麻醉下,对6只新生羔羊进行了颈动脉血流变化对颅内血流速度影响的研究。使用电磁血流袖带测量颈动脉血流。使用连续波和脉冲波多普勒组合仪器,通过人工制造的囟门测量颅骨基底的颅内血流速度。基线颈动脉血流为96±18ml·min⁻¹(平均值±标准差),对侧闭塞后增加58±13%。发现颈动脉血流变化与颅内血流速度之间存在密切相关性(y = -6.28 + 3.72x,Sy = 182.3,Sy/x = 0.30,r = 0.89,p < 0.001)。对脑血流变化的最接近估计是横截面平均速度的颞部平均值。