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一名2019冠状病毒病再次感染患者的血清抗体谱

Serum Antibody Profile of a Patient With Coronavirus Disease 2019 Reinfection.

作者信息

To Kelvin Kai-Wang, Hung Ivan Fan-Ngai, Chan Kwok-Hung, Yuan Shuofeng, To Wing-Kin, Tsang Dominic Ngai-Chong, Cheng Vincent Chi-Chung, Chen Zhiwei, Kok Kin-Hang, Yuen Kwok-Yung

机构信息

State Key Laboratory for Emerging Infectious Diseases, Carol Yu Centre for Infection, Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.

Department of Microbiology, Queen Mary Hospital, Hong Kong Special Administrative Region, China.

出版信息

Clin Infect Dis. 2021 May 18;72(10):e659-e662. doi: 10.1093/cid/ciaa1368.

Abstract

We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.

摘要

我们最近报告了一例2019冠状病毒病再次感染的患者。在此,我们表明在首次发病期间可检测到血清中和抗体,但在第二次发病时未检测到。在再次感染期间,住院后8天内发现了中和抗体和高亲和力免疫球蛋白G,而未出现免疫球蛋白M反应。

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